The drug "Nakom" instruction describes howcombined anti-Parkinsonics. The use of this drug at times enhances dopaminergic transmission and significantly reduces the manifestations of painful symptoms by converting the active component into dopamine by decarboxylation in the brain. In this case, the therapeutic effect of using the drug "Nakom" (the instruction confirms this) is manifested during the first 24 hours after admission. The greatest result is achieved seven days after the start of treatment. As for the half-life, it is between three and fifteen hours after the use of the anti-Parkinsonian drug "Nakom". Analogues of this medicine - capsules "Duellin", "Tremonorm" and "Sinemet" - have a similar mechanism of action.
Produced this drug in the form of ovalbiconvex blue pills. The composition of each dragee as active elements includes two hundred and fifty milligrams of levodopa and twenty-seven milligrams of carbidopa monohydrate. Auxiliary ingredients are microcrystalline cellulose, pregelatinized starch, magnesium stearate, corn starch and blue indigotine.
Take Nakom tablets instructions forapplication recommends for the treatment of people suffering from Parkinson's syndrome and disease. In addition, specialists quite often prescribe this drug to patients who use multivitamins containing pyridoxine hydrochloride.
Take an antiparkzonian drug"Nakom" instruction strictly does not recommend people with individual intolerance to levodopa and monohydrate carbidopa, as well as an allergic reaction to any other auxiliary constituents. In addition, the list of contraindications includes an angle-closure glaucoma, renal failure, melanoma, pregnancy and liver failure. Also, do not take this drug at the same time and non-selective monoamine oxidase inhibitors. In addition to all other contraindications are the age of eighteen years and the lactation period.
Among the most common adverse reactions,provoked by the drug "Nakom", experts distinguish skin rash, leukopenia, angioedema, anemia, agranulocytosis and thrombocytopenia. In addition, there is a risk of developing malignant melanoma, arterial hypertension, stomach ulcers and hematuria. Anorexia, insomnia, confusion, bruxism, hallucinations, sleep disturbances, psychotic seizures, disorientation, lethargy, paranoid thinking, paresthesia, headache, dyskinesia, seizures, ataxia and chorea can also be noted as a result of the Nakom tablets. The instruction also indicates the risk of dyspnea, bitterness or dryness in the mouth, delay of urination, loss of consciousness, increased sweating and sweating.