Increased body temperature indicatespathological processes occurring in the patient's body. If the heat is small and does not exceed the low-grade values, then it should not be eliminated by taking the tablets. If the temperature is very high, then it should be immediately knocked down. Otherwise, this can lead to serious consequences.
Modern pharmaceutical companies producea huge number of medicines that can quickly eliminate any heat. However, the most effective drug among them is the Pentaflucin medication. The composition of this drug, its analogs, method of application and form of release will be presented below.
What does the Pentaflucin preparation contain?Instructions for use (powder - this is the only form of this drug) reports that the active ingredients of the drug in question are ascorbic acid, paracetamol, calcium gluconate, rutin and diphenhydramine. As for additional elements, they use sugar, low molecular weight polyvinylpyrrolidone and essence.
The drug "Pentaflucin" is a white granule that is designed for dissolution. They are contained in bags of 5 g (for single use).
What is remarkable about Pentaflucin? Instructions for use (powder should be prescribed only by a doctor) reports that it is a combined medicine that has antipyretic effect.
This remedy is used to relieve the patient's condition for colds and flu. It has antipyretic and anti-inflammatory properties.
The effectiveness of the drug for adults and adolescents is due to the ingredients that make up its composition.
Paracetamol is a non-narcotic analgesics, which not only has an antipyretic action, but also carries a lock COX-1 and COX-2 in the CNS.
Acid ascorbic is involved in blood clotting and carbohydrate metabolism. It also increases resistance and promotes tissue regeneration.
Diphenhydramine, or diphenhydramine, has antihistamine action. It eliminates the swelling of the mucosa and its inflammation, has a sedative and hypnotic effect.
Rutozid, or rutin, reduces the fragility of capillaries, reduces blood clotting and is an antioxidant.
Calcium gluconate regulates calcium metabolism, normalizes the concentration of phosphorus in the plasma.
What pharmacokinetic parameters are inherentgranules of Pentaflucin? Instructions for use (the powder should be dissolved before use) states that paracetamol is rapidly absorbed from the digestive tract. Its maximum concentration is reached in about 30-55 minutes. It is instantly distributed in tissues and has a low bond with proteins. Metabolism of paracetamol is carried out in the liver, and is excreted by the kidneys.
The maximum concentration of rutoside is reached after 2-9 hours. Its half-life is 10-25 hours.
Ascorbic acid is also rapidly absorbed from the digestive tract. Its highest concentration is achieved after 4 hours. It is metabolized in the liver.
Dimedrol, or diphenhydramine, is rapidly absorbedin the blood. Its bioavailability is 50%, and the highest concentration is observed after 20-40 minutes. A large amount of this component is found in the lungs, liver, brain and kidneys. It penetrates the BBB, and in a day it is completely excreted by the kidneys and along with the mother's milk, which often causes sedation in children.
What is the treatment for adults and adolescents? This drug is good at elevated body temperature, with flu and colds.
About how to dissolve the powder "Pentaflucin", we will discuss further.
This medication is contraindicated:
Caution this drug is prescribed for congenital hyperbilirubinemia.
Powder designed to reduce temperaturebody, take inside only one sachet. This procedure is carried out three times or four times a day, before meals. Therapy with this remedy should last no more than 3-5 days.
How to dissolve granules for their reception?The contents of one packet are dissolved in 0.5 glasses of hot water, and then immediately taken internally. When preparing the solution, it is allowed to have a slight precipitate.
According to the instructions, it is not recommended to take the medication in question with the use of alcohol. It is also necessary to refrain from driving motor vehicles.
The medicinal powder "Pentaflucine", analogues of which are listed below, can cause the following undesirable reactions:
When taking the drug at high dosages, nephrotoxic or hepatotoxic effects may also occur.
The drug "Pentaflucin" is able to strengthenthe effect of funds that reduce blood clotting and reduce the aggregation of platelets. It also increases the side effects of non-narcotic analgesics, glucocorticoids, NSAIDs, sulfonylurea derivatives and methotrexate.
It should be avoided combining this drug with barbiturates, anticonvulsants, Diphenine, Rifampicin, Carbamazepine, alcoholic beverages and Zidovudine.
The price of Pentaflucin powder is 150-170 rubles. If required, it can be replaced with such drugs as Coldrex, Max Gripp, Antigrippin and Coldflu.
According to experts, this drugshould be prescribed only for symptomatic treatment of patients with respiratory diseases. All those who have repeatedly taken this medication note its high efficiency, acceptable cost and availability in pharmacies. Receiving one sachet of medicine almost immediately alleviates the patient's condition.
Among the shortcomings of the powder, such a sideaction, like drowsiness. Doctors explain this reaction by the fact that the composition of the medication is dimedrol. By the way, the drug "Pentaflucin diurnal" does not include this ingredient, so it is devoid of this effect.