The drug "Ksefokam" instruction refers tononsteroidal anti-inflammatory drugs with the active substance - lornoxicam (Lornoxicam). This product is available in two forms: oral tablets and powder for injections in the form of a solution. The proposed instruction is for the drug "Xefokam" in the form of powder for injections.
Form release and composition of the medicine "Xefokam"
Инструкция описывает препарат в виде сухого powder for the preparation of injection solutions of 10 cm³ in vials, which are packaged in packages of 1, 5 and 10 pcs. The kit is also available with a solvent (sterile water - ampoules of 2 cm³) and without it. One bottle contains 8 mg lornoxicam.
Pharmacotherapy of the drug "Xefokam"
The instruction informs about the expressed analgesic and anti-inflammatory action of the medicine.
Indications
It is used in case of moderate and severe pain syndrome in the following cases:
- Arthralgia, myalgia, neuralgia, pain in the spine, sciatica, lumbago, migraine, dental and headache, algodismenorea;
- pain with burns, trauma, cancer.
For symptomatic therapy of pain and inflammation in degenerative and inflammatory rheumatic diseases:
- rheumatoid arthritis, osteoarthritis, ankylosing spondylitis;
- articular syndrome, in case of an exacerbation of gout;
bursitis, tenosynovitis.
Contraindications to the use of Xefokam powder
Instructions prohibits preparation with:
- hypersensitivity to lornoxicam or other ingredients;
- the presence of hypersensitivity to acetylsalicylic acid or substances from the group of NSAIDs (ibuprofen, indomethacin) in the anamnesis;
- hemorrhagic diathesis or blood coagulation disorders;
- gastrointestinal ulcer in the phase of exacerbation;
- nonspecific ulcerative colitis;
- pronounced violations of the liver;
- moderate or severe renal dysfunction;
- hypovolemia or dehydration;
- confirmed or suspected hemorrhagic stroke;
- bronchial asthma;
- heart failure;
- decreased acuity of hearing;
- the period of pregnancy and lactation;
- the age of 18 years.
Xsefokam: instruction
The injections are done in / m or / in with pain inpostoperative period, with an attack of acute lumbago, ishalgia. The initial dose is 8-16 mg. The maintenance dose of the drug - 8 mg - two injections per day. The dose of the drug should not be above 16 mg / day.
Rules for preparation of medicine "Xefokam"
Инъекции готовят следующим образом:8 mg of the powder is dissolved in 2 cm³ of water for injection. The solution is injected in / in or / m. Ready-made rp must be entered within 24 hours. It is necessary to enter I / O at least 15 s, in / m - not less than 5 s.
Possible side effects
In the digestive tract and liver in the form:
- pain in the abdomen, diarrhea, dyspepsia, nausea, vomiting;
- rarely - flatulence, dry mouth, gastritis, esophagitis;
- the formation of peptic ulcers and / or bleeding in the gastrointestinal tract, stomatitis, glossitis, colitis, dysphagia,
- Hepatitis, pancreatitis, violations of liver function.
Possible manifestations of allergic reactions in the form of:
- skin rash;
- hypersensitivity reactions involvingtachycardia, shortness of breath, bronchospasm, Stevens-Johnson syndrome, exfoliative dermatitis, angiitis, fever, allergic rhinitis, lymphadenopathy.
В ЦНС редко в форме головных болей, dizziness, drowsiness, arousal, sleep disorders, tinnitus, hearing loss, dysarthria, hallucinations, migraine, peripheral neuropathy, syncopal states, aseptic meningitis.
special instructions
Care must be taken in applying for anemia and hypertension.
Interactions
When administered simultaneously with anticoagulant or inhibitory substances, platelet aggregation increases the risk of bleeding. WITH sulfonylurea derivatives may enhancehypoglycemic effect of the latter. With other NSAIDs or GCS - to increase the risk of developing negative manifestations in the gastrointestinal tract, and with diuretics - to reduce the diuretic and hypotensive effect. When used β-adrenoreceptor blockers and ACE inhibitors, the drug reduces their hypotensive effect.
Overdose
Perhaps the increased manifestations of the side effects of the drug "Ksefokam." Overdose treatment is symptomatic.
