Preparation "Ondansetron" instructions for usecharacterizes as an antiemetic, effectively suppressing the gag reflex, preventing and eliminating nausea. The action of this drug is based on a competitive highly selective blockade of peripheral and central receptors
serotonin.The highest effectiveness of this antiemetic drug in the postoperative period, as well as during the passage of radiation therapy and the admission of special chemotherapeutic drugs. However, in this case, it should be specially emphasized that frequent medication "Ondansetron" (instruction for use confirms this) can significantly slow the intestinal motility and passage of the contents through the digestive tract. As for its pharmacokinetic parameters, the largest plasma concentrations are noted one and a half to two hours after direct use, and the half-life takes about three hours.
The drug "Ondansetron" (instruction onapplication is obligatory is in the complete set) in the form of yellow oval tablets and in the form of a solution for infusions and injections. The composition of the first as the main element is ondansetron hydrochloride dihydrate in a volume of five or ten milligrams. In the role of additional components in this case are anhydrous lactose, magnesium stearate, pregelatinized starch, microcrystalline cellulose and yellow oparium. In the colorless transparent solution, the active element contains four or eight milligrams of ondansetron. Auxiliary ingredients are citric acid monohydrate, sodium citrate dihydrate, nitrogen, sodium chloride and purified water.
Use medicinal product "Ondansetron"the instructions for use recommend the elimination and prevention of vomiting and nausea in patients undergoing cytotoxic chemotherapy. In addition, the reception of this remedy is very effective in the postoperative period.
During the radiotherapy is also worthuse antiemetics "Ondansetron." Reviews at the same time indicate good results of its use as with daily irradiation of the abdominal site, and at a single, but with high doses.
To prescribe this antiemetic drugthe company-manufacturer categorically prohibits in case the patient has an allergic reaction to "Ondansetron" or individual intolerance of any of the components present in its composition. During the period of gestation (especially during the first three months), you should also not take Ondansetron. These pills should not be prescribed to younger patients and women breastfeeding. In addition, direct contraindications for use are serious abnormalities in the operation of the liver and surgical interventions on the abdominal cavity.
