/ / "Renipril": instructions for use, feedback

Renipril: instructions for use, feedback


When hypertension is often usedACE inhibitors. They effectively and smoothly reduce blood pressure. To this group of drugs is the drug "Renipril". Instruction for use recommends taking this remedy not only for hypertension, but also for chronic heart failure. Also, the drug helps to reduce the load on the myocardium when the left ventricular function is disturbed.

Composition and action of the drug

The active component of the drug isenalapril maleate. The substance suppresses the activity of angiotensin-converting enzyme (ACE). This prevents vasoconstriction. As a result, blood pressure is reduced. In addition, enalapril stimulates the formation of kinins and prostacyclin, which leads to vasodilation and creates an additional antihypertensive effect. This reduces the burden on the heart and improves blood circulation.

Enalapril somewhat reduces the activity of the hormone aldosterone, and therefore has a slight diuretic effect.

The preparation is produced in the form of white tablets.Each of them contains 10 or 20 mg of the active ingredient. Also in their composition are additional ingredients: povidone, sugar, starch and calcium stearate. These substances contribute to better absorption of the drug.

The preparation "Renipril GT" is also produced.It contains not only enalapril maleate, but also a diuretic hydrochlorothiazide. The hypotensive effect of this drug is stronger than that of the usual "Renipril." However, it is not recommended for heart failure.

Packages with

Tablets lower blood pressure approximately 1 hour afteruse. The cost of the drug is from 70 to 160 rubles. Their action lasts about one day. However, in order to maintain blood pressure in a stable state, you need to take this medicine for at least 2 to 4 weeks.

To achieve the desired effect in chronic heart failure, you need to regularly take tablets for at least 6 months.

Indications

The instruction of "Renipril" tablets informs,that this drug is indicated for arterial hypertension of any etiology. The medicine is also prescribed for patients with chronic heart failure. In this case, it is used as part of complex therapy. With prophylactic purposes, tablets are recommended for patients with a violation of the function of the left ventricle of the heart.

How many tablets to take and at what pressure?The instructions for the use of "Renipril" do not indicate specific parameters of blood pressure, in which it is necessary to remove hypertension with the drug. This medication is used to treat various degrees of hypertensive disease. The dosage of the drug is determined by the attending physician depending on the severity of the symptoms of hypertension.

Arterial hypertension

Contraindications

These pills can not be taken by pressure from all patients. Instructions for use "Renipril" prohibits the use of the drug in the following diseases and conditions of the body:

  1. The drug is contraindicated in case of an allergic reaction to any of its components. If the patient has an increased sensitivity to sulfanilamide drugs, then "Renipril" should also not be taken.
  2. The drug is not prescribed for severe violations of kidney and liver function.
  3. If a patient undergoes a kidney transplant in the past, the use of these pills against pressure is prohibited.
  4. The drug is contraindicated in the excess production of the hormone of the adrenal gland - aldosterone.
  5. Severe blood disease - porphyria is also an absolute contraindication.
  6. The drug is not used to treat children and adolescents under the age of 18 years.
  7. When pregnancy and lactation, take this medicine is prohibited.

In some cases, the drug should be used at a reduced dosage under constant medical supervision. Caution is necessary in the following pathologies and conditions:

  • diseases of the adrenal glands;
  • hyperkalemia;
  • leukemia;
  • stenosis of the arteries of the kidneys;
  • diabetes mellitus;
  • autoimmune diseases;
  • violation of hematopoiesis;
  • cerebrovascular disease of the brain;
  • elderly patient (over 65 years of age).

In addition, caution should be observed if the patient simultaneously with "Renipril" takes diuretics from the group of saluretics and immunosuppressors.

Undesirable effects

Most patients tolerate this drug well. However, the instruction "Renipril" warns about the possibility of the following undesirable effects:

  • dry cough;
  • tachycardia (with simultaneous intake of diuretics);
  • dizziness when changing the position of the body;
  • dyspeptic phenomena (nausea, abdominal pain, diarrhea, or constipation);
  • violations of the liver and pancreas;
  • allergic reactions (skin itching, edema Quincke);
  • anxiety;
  • sleep disorders;
  • abnormalities in the clinical analysis of blood;
  • photosensitization;
  • violations of water-electrolyte exchange;
  • decreased libido;
  • impotence;
  • tides;
  • baldness.

The recommendeddoctor dosage of the drug. Exceeding the prescribed number of tablets may lead to a sharp drop in blood pressure and arrhythmia. In case of an overdose, it is necessary to rinse the stomach immediately, give the patient an enterosorbent and call a doctor. Treatment arisen arterial hypotension is carried out by introducing a solution of sodium chloride.

Overdose of

How to take pills

Instructions for the use of tablets "Renipril"reports that this drug can be taken as before meals, and after. The dosage of the medicine is selected by the physician individually, depending on the severity of the symptoms of hypertension and BP indices. Treatment for hypertension is started with 1 tablet (10 mg) per day. Maximum of a day prescribed no more than 80 mg of the drug.

If heart failure is treated, 2.5 mg of drug per day is prescribed at the beginning of therapy. Then increase the dose to 10-20 mg per day.

special instructions

Instructions for using "Renipril"warns about the inadmissibility of drinking alcohol during treatment. Ethanol enhances the effect of ACE inhibitors. Joint intake of the drug from pressure and alcohol can cause a sharp drop in blood pressure, up to a collapse.

During treatment it is better to refrain from drivingcar and performing complex works. This recommendation is due to the fact that during the first days of therapy the drug may cause dizziness due to lowering blood pressure.

Interaction with other drugs

The instruction on the application of "Renipril" informs aboutthat this drug is able to interact with other drugs. Particular care should be taken when taking the tablets from the pressure with the following drugs:

  1. Analgesics, antipyretic, anti-inflammatory and estrogenic drugs, as well as "Eufillin." These drugs reduce the effect of the drug on pressure.
  2. Anesthetics, diuretics, beta-blockers and calcium channel blockers. Perhaps a sharp drop in blood pressure and arrhythmia with a joint admission.
  3. Preparations with lithium. Their removal from the body slows down when used together with "Renipril".
  4. Sulfonamide. The risk of developing an allergy increases.
  5. Immunosuppressants and cytostatics. These medicines increase the toxicity of the drug.

Storage, price and analogy

Tablets should be stored at a temperature of not more than +25 degrees. They are usable for 4 years. The price of the drug in pharmacy chains is from 25 to 130 rubles.

You can choose the structural analogues of the drug. which contain the same active substance. These include:

  • "Enalapril";
  • "Enap";
  • "Berlipril";
  • "Normapress";
  • "Renitek".

Which drug is more effective:"Enalapril" or "Renipril"? This question is often asked by patients. The active component of these two drugs is absolutely the same. They differ only in the manufacturer and some additional ingredients. The price of "Enalapril" is from 10 to 200 rubles.

Reviews about the medicine

You can meet many positive reviews about"Reniprile". Patients report that this medication acts gently. It lowers the pressure smoothly, without sudden fluctuations. In this case, the drug does not cause a drowsy condition, it can be taken during the working day.

However, part of the patients had dry coughafter taking "Renipril". Instructions for use and reviews report such an undesirable effect. Usually this phenomenon passes independently.

Patients also report dizziness andweakness after taking the drug. Such symptoms are associated with lowering blood pressure and disappear as the body adapts to the drug. If undesirable manifestations persist for a long time, then it is necessary to consult a doctor about the dosage reduction and replacement of the drug.

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