Urea is the final product of disintegrationproteins. It is excreted from the body through the kidneys. The work of the kidneys is analyzed by the amount of urea in the blood and in the urine. If urea in the blood is increased, then you can talk about acute and chronic kidney disease. Due to insufficient work of the body, urea accumulates in the blood. Consequently, its urinary index decreases.
Protein metabolism in the body is quite complicateda process in which one part of the proteins undergoes disintegration, the other forms a new form. The decomposition of proteins is accompanied by the release of a toxic substance - ammonia. Urea is formed from ammonia in the liver. Then it is excreted in the urine through the kidneys. The excretory power of the kidneys can be judged by the concentration of urea in the blood and the rate of its excretion from the body. By the factor of synthesizing the component in the liver, reducing it in the blood suggests a liver disease. It can be cirrhosis.
Proteins in the human body are contained, inmostly in the muscles. If the process of protein breakdown in muscles accelerates, then urea in the blood is increased. Its indicator characterizes the work of muscles, liver, kidneys. The concentration is determined by a biochemical blood test in a laboratory. For this, blood is taken from the vein in the morning, on an empty stomach.
Even if urea in the blood is increased, it is notalways speaks about the presence of any disease. The indicator can also increase in perfectly healthy people who take in food, mainly foods rich in protein: meat, legumes. In addition, physical activity gives the same effect.
Diseases in which urea in the blood is increased
The concentration of urea in the blood increases inthe result of the following diseases: pyelonephritis, glomerulonephritis, amyloidosis of the kidneys. The symptoms of the organ are indicated by: a violation of urination, increased blood pressure, fatigue, general weakness, traces of blood in the urine. Analysis shows that urea is increased. In addition, in diseases that result in impaired blood access to the kidneys, urea in the blood is also increased. Deviation of the component from the norm may occur due to heart failure, high degree burns, bleeding. The pathology is caused by incomplete purification of the blood by the kidneys. Such diseases as tumors, thyrotoxicosis affect the increase in the breakdown of proteins, and consequently, the increase in urea.
Urea in urine
According to the content of urea in urine, one can judgecause of its increase in the blood. If the analysis did not reveal deviations from the norm, then urea in the blood is increased not because of kidney disease, but because of a violation of blood flow to the organs (kidneys). This factor indicates other diseases, perhaps, the heart. Decreased urea in the urine indicates kidney disease.
Urea in urine is obtained by laboratorymethod. For analysis, it is required to collect a daily dose. During the collection period, you should use liquid as usual. The adoption of meat products - limit. With an increase in the breakdown of proteins, the urea index in the urine increases. Pathology occurs with the following factors: a large amount of protein coming from food; hormonal failure of the thyroid gland; postoperative condition.
Reduction of urea in urine occurs in children,vegetarians, pregnant women, people in the postoperative period. Diseases that lead to a decrease in urea in the urine are: cirrhosis, hepatitis, malignant liver tumors, kidney failure, pyelonephritis.
In order to maintain their own healthit is necessary to periodically examine the blood and urine. If you see a change in the urea index, you should immediately contact a specialist. Increase or decrease of urea in blood and urine indicates the presence of diseases of several organs. An accurate diagnosis is needed, which establishes the main cause that led to pathology. With properly prescribed treatment, the results of the analyzes are normalized.
