The drug "Deprenorm MB" is amodified release medicament. The active component is trimetazidine dihydrochloride. The drug "Deprenorm" instructions for use refers to the category of antianginal drugs that improve myocardial metabolism. The drug has an antihypoxic property.
The drug directly enhances the activity andmetabolism of cardiomyocytes and neurons in the brain. Due to rationalization of oxygen consumption, increase of energy potential, activation of oxidative decarboxylation, cytoprotective action is carried out. Characterizing the drug "Deprenorm", the instruction indicates its properties to maintain normal contractility in the myocardium, prevent intracellular depletion of creatine phosphate and ATP. Under the action of a medicament under conditions of acidosis, the state of membrane ion channels is normalized, the level of potassium ions inside the cell is normalized. The drug prevents the accumulation of sodium and calcium in cardiomyocytes. The drug "Deprenorm" (instructions for use contains such data) reduces the level of phosphates, reduces acidosis inside cells, prevents the damaging activity of free radicals, ensures the integrity of cell membranes. In addition, the drug helps to increase the duration of the electrical potential.
As specialists note, when applyingmedication with angina reduces the frequency of seizures and reduces the need for nitrates. Two weeks after the start of therapy, exercise tolerance increases, and pressure drops (arterial pressure) decrease. The drug "Deprenorm" (reviews of many patients indicate this) contributes to improving hearing, reducing the noise in the ears. In addition, dizziness decreases. On the background of vascular pathologies of the eyes there is an improvement in the functional state of the retina.
Drug "Deprenorm" instructions for userecommends for chorioretinal vascular disorders, cochlear-vestibular disorders of ischemic origin (hearing impairment, tinnitus). The drug is indicated in dizziness of the vascular nature, as well as to prevent attacks of angina (in combination with other drugs).
Medication "Depenorm" instructions for usedoes not admit to prescription for renal failure, expressed disorders of the liver, pregnancy. Contraindications include individual intolerance, childhood (up to eighteen years), breastfeeding.
The drug is taken orally.Dosage - seventy milligrams (two tablets), divided into two doses. Duration of treatment is set for each patient individually. Tablets should be taken with food.
The drug "Deprenorm" can cause vomiting,nausea, gastralgia and other disorders of the functions of the gastrointestinal tract. In some cases, itching, dizziness, and headache may occur. As practice shows, and numerous reviews of patients testify, these adverse reactions are rare.
The drug is not intended to eliminate attacks of angina pectoris. If you have or experience seizures, you should see a doctor. Probably, in this case correction of the treatment scheme will be required.
In the course of the research, the effect of the drug on the ability to work with equipment, mechanisms or driving was not revealed.
The expiration date of the "Deprenorm" remedy is two years. Do not take medication after the specified time.
Before taking the drug, "Deprenorm" should consult a doctor.