The drug is produced in 3 medicinal forms- suspension, dispersible and conventional tablets. Suspension of a pleasant smell, with a shade of yellow color and a rather characteristic taste for this preparation. The suspension can be redispersed when the vial is shaken.
Tablets are produced in almost white color, with a slight yellowish tinge. Tablets of round shape, biconvex, both of its surfaces are smooth.
Pharmacological action of the drug
Pharmacological action belongs to the firstturn to nayz - tablets, the instruction contains data on all dosage forms. The drug is an NSAID containing a sulfonylidic moiety in its structure. Nimesulide, possibly, belongs to inhibitors of COX-2, as a result of which it has anti-inflammatory and analgesic effects, in addition, the drug has analgesic effects, but to a lesser extent.
The mechanism of action of the drug is associated with the suppression of the synthesis of prostaglandins in the inflammatory region, as well as suppression of the formation of oxygen radicals and inhibition of the release of myeloperoxidase.
Naise is perfectly absorbed from the digestive tract, reaching its maximum in the blood after 2 hours. The drug is 99% bound to proteins.
The drug Nise - tablets, instruction about which is taken from official sources, is metabolized in the liver, and is excreted from the body with urine, and 98% of the received dose is excreted within 24 hours.
Side effects naz
Tablets, the instruction to which is now given, can give side effects in various systems and organs:
Side effects of the drug, which are related to the digestive tract
Side effects of the drug, which are related to the central nervous system:
Side effects of the drug, which are allergic reactions:
Other side effects:
There is a list of contraindications, in which it is recommended to avoid taking the drug, and if necessary, only after consulting a doctor.
Drug Interactions Nase
Tablets, instructions for the use of which are notHere is the full and comprehensive data of all drug interactions drug, reads as follows: is not recommended with the following drugs - phenytoin, digoxin, any diuretics lithium medications, anticoagulants, antihypertensives, NSAIDs, methotrexate, cyclosporine.