Dioxydin instructions for use refer toClinico-pharmacological group of drugs that have antibacterial action. The main substance, which provides the action of the drug - hydroxymethylquinoxaline dioxide, which is derived from quinoxaline.
The form of the release is a solution of Dioxydin, whichis a liquid of light yellow, to a greenish shade, intended for intravenous administration. Ampoules Dioxydin are available in volumes of 1 and 5 milliliters.
The composition of the drug as an auxiliary substance is water for injection.
The pharmacological action of Dioxydin is based onits high chemotherapeutic activity at suppression of infectious phenomena that causes a wide spectrum of application of a preparation. It is effective in the fight against dysentery bacillus, salmonella, Pseudomonas aeruginosa. Dioxydin is prescribed in cases of affection with staphylo- and streptococci, various pathogens of gangrene, the drug effectively affects some strains of bacteria that show resistance to other antibiotics and chemotherapy drugs.
Medicinal preparation Dioxydin instruction recommends the introduction of intravenously with strict adherence to the established dose, because in small doses, its therapeutic effectiveness is relatively small.
Pharmacokinetics of the drug is characterized byfollowing properties. After intravenous administration of the drug, its therapeutic concentration remains in the patient's blood for four to six hours. In this case, the medicine quickly enters various tissues and organs. With repeated administration, the amount of medicine in the body does not accumulate, and it is excreted well by the kidneys.
Dioxydin, the instruction to which recommendsinject the drug intravenously, previously diluted with 5% solution, which may be dextrose or 0.9% -concentrated sodium chloride solution.
As a rule, the daily dose of the drug is administered by two methods: either once or by fractional administration 3-4 times a day. The rate of droplet injection is 60-80 drops per minute.
The dose of administration is determined by the level of localization of the inflammatory process. 200-400 milligrams of the drug Dioxydin, the instruction recommends the use of purulent infections of the urogenital organs.
In the treatment of chronic lung diseases with a purulent course of the disease, the dose per day can be 500-600 mg, and in the treatment of purulent meningitis - 600-700 milligrams per day.
In cases of severe septic lesions, the dose of the drug can be increased to 600-900 mg per day for 3-4 injections.
Categorically contraindicated use of the drug during pregnancy and during lactation.
Use of the drug has side effects: headache, allergic reactions, chills. Less common are cases of fever, seizures, photosensitizing effect.
Please note: Dioxydin in the nose instruction does not recommend applying! This drug is not prescribed for children at all.
Storage of the drug provides for compliance withstandard conditions: a place without access to light, the temperature should be between 18 ° and 25 ° C. If these conditions are met, the expiration date of the medicinal product is 2 years.
Particular caution in the appointment should be shown to patients suffering from
renal failure, in which case the dosethe administration of the drug should be reduced. The same should be done with the appearance of pigment spots on the body, it is also possible to additionally prescribe antihistamines.
The drug in pharmacies is realized only if there is a prescription for a doctor.
