What is a drugMydocalm? What helps this tool? Indications and features of the considered medication, we present below. You will also learn how to treat this drug, how much it costs and what its composition is.
In what form does the drug come to pharmacies"Mydocalm" (what does this medicine help, we will tell below)? This tool is available in tablets, as well as in a solution intended for parenteral administration.
Round and white tablets "Mydocalm", the price of whichindicated below consist of tolperisone hydrochloride. The following ingredients are included as an additional ingredient: anhydrous colloidal silicone, citric acid monohydrate, corn starch, stearin, hydroxypropyl methylcellulose 2910, talc, macrogol 6000, microcrystalline cellulose, dye, lactose monohydrate, and titanium dioxide.
This means is issued in blisters which are placed in boxes from paper.
Clear solution "Mydocalm" in ampoules alsocontains tolperisone hydrochloride and lidocaine. In addition, this medicine includes the following components: talc, citric acid monohydrate, lactose monohydrate, anhydrous colloidal silicone, macrogol 6000, microcrystalline cellulose, stearin, titanium dioxide, corn starch, black ferric oxide, hydroxypropylmethylcellulose 2910, red ferric oxide and yellow iron oxide.
The drug "Mydocalm" in ampoules is contained in plastic containers that are placed in cardboard boxes.
What is the "Mydocalm"? What does this drug help? According to the instructions, the agent in question relates to the muscle relaxants of the amino ketone group, which has a central effect.
The effectiveness of this medication is related toregulation of the work of the (caudal) reticular formation. The use of this medication contributes to the inhibition of increased reflex excitability of the spinal cord. It also affects the nerve endings (peripheral).
The drug "Mydocalm" (compatibility of thisfunds with other valid, but under special conditions) is an H-anticholinergic. Its active substance has a stabilizing effect on the membrane in the primary fibers (afferent), as well as motor neurons. This effect of the medication is due to its ability to affect the reflex work of spinal synapses.
It should also be noted that this drugsecondarily slows down the removal of mediators. This is due to the inhibition of the process of calcium in the synaptic structures that are in the nerve fibers.
The effect of this remedy on the reticulospinal pathmanifested especially pronounced when slowing the processes of excitation. Similarly, the local-anesthetic effect of the drug is revealed (due to its lidocaine content).
The considered agent is well absorbed fromintestine. Its concentration (maximum) in the blood is reached 65 minutes after administration. Metabolism of the drug occurs in the kidneys and liver. Derivatives of tolperisone are excreted in the urine.
Repeated course "Mydocalm" has no effect on the work of the kidneys and liver, as well as the process of blood formation.
This tool reduces experimentallycaused by rigidity and hypertonicity of muscle tissue. The therapeutic properties of this drug are actively used to reduce muscle stiffness and pathological hypertonia, which are associated with extrapyramidal disorders.
It should also be noted that this drugcontributes to the activity of the person (his movements). In addition, it does not affect the cerebral cortex in any way, fully preserving the patient’s waking level.
According to the instructions, treatment with Mydocalm causes slightly pronounced antispasmodic and adrenoceptor blocking effects. Due to this, tissue perfusion improves.
In the process of conducting long-term clinical studies, this tool did not have a pronounced effect on blood formation and kidney function.
This tool is shown for use in the following cases:
In what cases it is impossible to prescribe tablets and injections "Mydocalm"? The use of this medication is contraindicated in:
The scheme of use of this tool is determined by the doctor depending on the course of the disease, as well as the tolerability of the drug.
Для взрослых людей медикамент назначают в the amount of 150-450 mg (daily dose) in three doses. The starting dosage of this medicine is 50 mg three times a day. With insufficient efficiency it is increased.
For intramuscular injections, the drug is used inthe amount of 200 mg per day (in two administrations), and intravenous - 100 mg (once a day). In the second case, a very slow infusion of the drug is required.
For children older than three months (up to 6 years)The dosage of the medication in question is calculated according to the following scheme: 5-10 mg per kg of body weight (three times a day). For a child of 7-14 years, it is recommended to use tablets in a daily dose of 2-4 mg per kg of body (three times a day).
Oral administration "Mydocalm" must be combined with food intake.
Taking the drug with individual hypersensitivity can cause weakness in the muscles, dyspeptic symptoms (nausea, discomfort and vomiting), as well as headaches.
With rapid intravenous infusion of a solution may decrease blood pressure.
If you are hypersensitive to medication, allergic reactions develop. As a rule, with a decrease in the dose of the medication, side effects disappear very quickly.
Interaction Information, which limitsuse of the considered drug is not available. However, it should be noted that tolperisone has an effect on the central nervous system. In this case, the drug does not cause drowsiness, so it can be combined with hypnotic drugs and sedatives, as well as medicines containing ethanol.
While taking "Mydocalm" enhances the effect of niflumic acid. If necessary, the combination of such funds may require a decrease in the dose of the latter.
Peripheral muscle relaxants, drugs for general anesthesia and psychotropic drugs, as well as clonidine, enhance the effectiveness of tolperisone.
How much is "Mydocalm"? The price of this tool is about 185 rubles.
Patient testimonials state thatThe medication in question manifests itself very effectively, especially in diseases of the joints. In addition, this tool is well helps with impaired blood circulation in the brain, including those that have arisen after a traumatic brain injury.
Among the negative reviews can be identified those that say that the drug "Mydocalm" is not a panacea. Most often, this medicine is used as a maintenance treatment.