Oncological diseases are the worsta reality for the absolute majority of people. But in order to identify a serious problem in time and begin to get rid of it effectively, it is necessary to conduct special examinations. One of them - IHH-study.
The exact causes that make cells activelyto share, forming neoplasms, often with oncological orientation, science is still unknown. But here is how cell growth occurs, is already quite well understood. Tissue cells have a complex structure. On the surface of the cell there is a so-called HER-2receptors. They serve as a kind of antenna, listening to the commands of the body. By the way, the abbreviation HER-2 originates from the English phrase human epidermal growth factor receptor 2that literally means "receptor of human epidermal growth factor". These receptors also force the cell to divide, grow, or self-repair.
Unfortunately, not always the human body works as it should ideally be, without failures and illnesses. So far science does not know exactly why, but it happens that HER-2receptors begin to actively receive commands"share and multiply." And since these cellular elements are very efficient, they force the cells to actively divide, forming a tumor. Only medical examinations, including IHH-investigation, allow to determine the status of the tumor, as well as the prognosis for the treatment and life of the patient.
Oncological education with modern medicinedetermined by the status of the influence of hormone therapy. This status can be negative (negative) and positive (positive). Specify the nature of the tumor helps IHH-исследование.What does immunohistochemistry show? This study helps to establish the hormone dependence of the neoplasm - hercept status, and therefore, choose the right treatment method to get an effective result.
The fact that the hormonal status of the tumor is wearingthe names "positive" or "negative" will tell a lot to a competent doctor. But by themselves, these definitions do not refer to emotions, as a simple man in the street who first heard about IHG research might think. The identified positive hercept status indicates that this type of cancer is more aggressive, it develops faster, spreading through the body by metastasis. But at the same time, such a malignant tumor with a high level of probability will respond to certain types of drugs. The negative hercept status of the neoplasm will tell you that the tumor develops slowly, but there is no adequate drug treatment for it yet.
One of the most common cancersamong women, breast cancer. IHH-research helps to determine the type of neoplasm and select the treatment in accordance with the situation. Immunohistochemistry is a laboratory study of a biopsy (a biomaterial taken in the biopsy process) using a special staining agent. This substance colors HER-2receptors, and the more receptors that affect the appearance and development of an "abnormal" cell, the brighter will be the color of the biomaterial under study.
Dyed biomaterial during laboratorystudies on the definition of Hercept status are subjected to visual research. for this purpose, a special scale is applied, having a gradient color from 0 to 3+. This method allows you to distinguish 4 main threshold, depending on which it is assumed to lead the patient further. It seems - what is easier? Color the test tissues with a special substance, place under a microscope, carefully consider, comparing what they saw with the control color samples, and establish the hercept status of the tumor. But here the human factor, lighting features and so on plays a huge role.
If an oncological disease is suspected breast research. Decoding immunohistochemical research contains only four thresholds. But the problem is that the average two values, which will be 1+ and 2+ on the scale, suggest an unclear result that requires additional research by another method. That is IHH-research is the most ambiguous methodidentify hercept-status tumors. In addition, the result of the study is actively influenced, as already mentioned, by the human factor and external circumstances. The only thing that is most accurately determined by the two extreme results is negative 0 (the tumor has a negative hercept-status) and 3+ (the hormonal status of the tumor is positive).
As modern medicine says, mosttumors of the female genitalia are dependent on the hormone levels of the body. Their development is actively influenced by female sex hormones - progesterone and estrogen. Receptors for these hormones determine the formation and development of cancer. The established hormonal dependence allows one to quite clearly determine the treatment regimen with the subsequent life prognosis. In addition, these receptors play a role not only in breast cancer, but also in such serious problems as female infertility, endometriosis and cancer diseases of the genital area - the uterus, ovaries, cervix. Hercept-status of the tumor, which is established during IHH-endometrial examination, for example, will allowprescribe treatment with exactly those drugs that will help to achieve an adequate result without undue experimentation with the selection of drugs in each case.
Infertility is a huge problem for manymodern families. Studies conducted by scientific medical institutions have shown that in quite a large number of cases, infertility is caused by a lack of endometrial hormonal background - the epithelial layer lining the uterus. It is the Hercept status that makes it possible to reveal IHH-исследование рецептивности эндометрия.Female sex hormones are active parts of the process of egg formation, fertilization, implantation of the embryo into the uterus, and subsequent gestation of pregnancy and childbirth. The IHG study of the endometrium, as we have already said, allows us to identify the hercept status of endometrial cells to estrogen and progesterone and, in accordance with the results obtained, select the right treatment for the woman.
Cancer is the misfortune of mankind.Although modern pharmacology and technical development can be cured of these diseases. But diagnosis is very important here, especially in the early stages of the disease. Oncology of lymph is a fairly common problem. An IHC study of lymphoma is one of the ways to make an accurate diagnosis so that you can prescribe adequate therapy. This study is performed on a biopsy of lymphatic fluid or tissue of the hematopoietic system. The material taken for the study is subjected to staining with special substances that help determine tumor markers. Unfortunately, this type of research is imperfect and in most cases supplemented with other diagnostic methods. In addition, the lymphatic system itself is often not the cause of the problem. This is exactly what makes it possible to reveal the IHC-lymphatic examination.
Health problems must be detected and identified on time. For this and need all sorts of methods of surveys, analyzes. IHH-research is one of the most commonmethods of diagnosing tumors or other problems with the tissues of various organs. The IHC study is carried out on the material taken to determine the problem - the so-called biopsy. The material is stained with special substances for each specific purpose, and by means of a visual comparison conducted by a histologist, tumor markers are established, showing one or another problem. The imperfection of immunohistochemical research is that the material may not be enough, the human factor will play its role, or external factors will not allow to establish an accurate picture of the problem. In any case, for an adequate diagnosis of the disease, especially of cancer, it is necessary to conduct a whole range of examinations, where one of the steps will be IHHstudy. What is it with cancer? any organ or tissue?The biopsy sample is examined for tumor markers, allowing to assess their presence in the sample. As an aid in making a diagnosis, IHC research is indispensable, it is also actively used in determining the causes of female infertility.
Medicine, and diagnostic including,constantly evolving. Perhaps in the near future, immunohistochemical research will be brought to perfection and will allow many people to make an adequate diagnosis with the least amount of time and effort.
