The drug "Hydrocortisone" (suspension) has anti-shock, anti-inflammatory, desensitizing, anti-allergic, immunosuppressive, antitoxic and antimetabolic effect.
The drug promotes an increase in bloodconcentration of glucose, the deposition of glycogen in the liver, slows the excretion of water and Na +, increases the secretion of K +, lowers histamine synthesis. The drug "Hydrocortisone" (suspension) reduces inflammatory cell infiltrates, migration of lymphocytes and leukocytes to the site of inflammation. The use in large doses inhibits the development of connective and lymphoid tissue, the increase in mast cells in which hyaluronic acid forms, suppresses hyaluronidase and reduces capillary permeability. The drug "Hydrocortisone" accelerates the breakdown and delays the synthesis of proteins.
When it is used, production is inhibitedcorticotropin due to influence on the pituitary gland. Prolonged administration can cause atrophy and suppression of the adrenal cortex, the formation of thyroid-stimulating and gonadotropic hormones.
Hydrocortisone acetate has an effect,developing slowly, but persisting for a long period, in contrast to water-soluble drugs. The medication is applied when injected into damaged areas, soft tissues and joints. In these areas, the drug "Hydrocortisone" (suspension) has an anti-inflammatory effect locally. However, systemic hormonal effects are also possible. Intra-articular administration causes a curative effect within six to twenty-four days, which lasts for several days (or weeks).
The injections of hydrocortisone phosphate can quickly suppress inflammation for a short period. This form of the drug is used in acute conditions.
The drug "Hydrocortisone" (suspension) is shown inin case of treatment failure in case of shock of different origin (traumatic, burn, surgical, cardiogenic, toxic). The drug is used for bronchial asthma in severe form, thyrotoxic crisis, systemic diseases in the connective tissue (rheumatoid arthritis and others), acute adrenal insufficiency, hepatic coma, acute hepatitis. The drug is prescribed for allergic reactions in severe, acute forms, anaphylactic and hemotransfusion shock, brain edema (including, associated with surgery, in the background of a tumor, trauma or radiation therapy). To reduce inflammation and prevent cicatricial contractions, the drug is used for poisoning with cauterizing liquids.
Drug "Hydrocortisone" is contraindicated forarticular administration in the case of previous arthroplasty, with intraarticular fracture, infectious inflammatory process, pathological bleeding. The drug is also not used in cases of marked periarticular osteoporosis, no signs of inflammation, severe bone destruction and deformity, instability due to arthritis, and necrosis of aseptic character in the epiphysis of the bones. Suspension is not prescribed in the post-vaccination period (before vaccination for eight weeks and after it for two), in case of immunodeficiency (including AIDS), and lymphadenitis after BCG. Do not use the drug for ulcerative pathology in the stomach and duodenum, latent (hidden) or acute peptic ulcer, gastritis, esophagitis, diverticulitis, ulcerative colitis with the risk of perforation or abscess, recently created intestinal anamostosis.
Before using the product "Hydrocortisone" (emulsion), you must carefully study the instructions and consult with your doctor.
Кроме жидкой формы, существует и препарат в виде ointment. As practice shows when applied externally, the effect is equally high, regardless of the form in which the drug "Hydrocortisone" is used. Reviews of some experts in relation to the drug positive. In particular, British doctors recommend the drug outwardly in the treatment of children's atopic dermatitis.
