Heart and vessel problems most oftenoccur in the elderly. But often these diseases occur in quite young patients. To improve the condition of the patient, doctors often prescribe cardiotonic agents. One of them is the drug Dobutamine. Instructions for use, release form, analogs and properties of the mentioned drugs are presented below.
Drug "Dobutamine", instructions forthe use of which is contained in a pack of thick paper, contains a substance such as dobutamine hydrochloride, and various auxiliary elements.
This drug is marketed as a colorless or slightly yellowish transparent solution for infusion, which is placed in glass ampoules.
Also, this medicine can be purchased in the form of a lyophilisate and concentrate for solution preparation.
Что представляет собой медикамент «Добутамин»?Instructions for use (in ampoules this medicine can be purchased at any pharmacy) states that it is a cardiotonic agent, synthetic catecholamine and beta-1-adrenomimetic.
This drug is able to stimulate the beta-1-adrenoreceptors of the myocardium, increasing its contractility. It also increases the minute and impact volumes of the heart and decreases the vascular OPS.
After applying the medication in questioncauses a moderate increase in heart rate. Chronotropic effect of the drug, as well as its positive dromotropic effects occur when using higher dosages.
In moderate doses, this medicine is weak.affects blood pressure. Due to the fact that he has a rather short half-life, it should be administered continuously. But it should be borne in mind that continuous therapy with this drug for 72 hours or more contributes to addiction.
The use of the drug Dobutamine, the instructions for use of which are described below, is necessary while monitoring the ECG, heart rate and blood pressure.
How long does it take?drug "Dobutamine"? Instructions for use (pills - the drug has no such form) reports that after intravenous infusion, the effect of this drug is observed after 2 minutes. Its steady plasma concentration is reached after another через hour.
The half-life of the drug is 2-5 minutes.
Do you know about the cases when the drug Dobutamin is prescribed? Instructions for use reports the following indications:
In some cases, do not prescribe a cardiotonic drug such as "Dobutamine"? Instructions for use (analogues of the drug are listed below) reports the following contraindications:
For newborns, this medicine is used for particular reasons. The same applies to minor children.
As well as analogues of this drug, "Dobutamine" is intended only for intravenous administration. In this case, it is pre-diluted with Ringer's solutions, 5% glucose or sodium chloride.
The finished medication is stored no more than a day.The speed and duration of its introduction depend on hemodynamic parameters. In this regard, the patient’s condition requires regular monitoring. It is necessary to monitor heart rate, blood pressure, as well as cardiac output (if possible).
So in what dosage prescribed "DobutamineHexal? Instructions for use informs that this remedy is administered to adults in the amount of 2.5-10 mg / kg / min (in rare cases - 40 mg / kg / min.). As for children, they are prescribed the drug in a dose equal to 1-15 mg / kg / min.
What negative reactions can the drug Dobutamine cause? The instructions for use indicate the possible occurrence of the following effects:
All adverse reactions of the vessels and the heart depend on the dosage used. As a rule, they disappear after the termination of the infusion or with a decrease in its speed.
How much is Dobutamine Hexal? Instructions for use does not answer this question. In pharmacies, the price of this drug may be about 350-450 rubles.
What should replace the medication in question? Its counterparts are the following drugs: Dobuzhekt, Dobutamin Solvay, Dobutamin Giulini, Dobutrex, Dobutamin Lahema, Dobutamine Nicomed.
Consumer reviews on the subjectThere is no drug. This is due to the fact that such cardiotonic agents are used only in emergency situations (for example, in acute heart failure, if the cardiac index falls and the contractile work of the left ventricle decreases). Typically, this condition is observed in cardiomyopathy, septic shock, myocardial infarction and open heart surgery.
According to experts, the medication in question is the basis of pharmacological therapy for cardiogenic shock. It is not used to treat chronic heart failure.
Since this medication can cause arrhythmia and tachycardia, it should be used for a short period of time and only in severe cases, that is, in acute heart failure.
It should be noted and the fact that this drug has a relatively small range between toxic effects and therapeutic doses.
Unlike the drug "Dopamine", it never causes vasodilation.
