How much does Monural help?Few women know the answer to the question. In this regard, in the presented article, we decided to tell you about what the mentioned medication is used for, how and through how much it acts, whether it has contraindications and so on.
About how much Monural helps youlearn from the instructions that come with the drug. It is placed in a cardboard box containing laminated multi-layered bags of medicinal substance.
The drug under consideration goes on sale in the form of white granules with tangerine flavor. They are designed to prepare a solution for oral administration.
The answer to the question of how much helps"Monural" is closely interrelated with its composition. The active substance of this drug is fosfomycin trometamol. It also contains additional components in the form of saccharin, tangerine and orange flavoring, as well as sucrose.
Many patients to whom this drug has been prescribed are interested not only in the question of how much Monural acts, but also in whether it is an antibacterial agent.
According to the attached instructions consideredthe drug is a modern broad-spectrum antibiotic. It is used in the treatment of many inflammatory diseases of the urinary system.
Before answering the question of whetherhow much Monural helps, it should be said that it is a derivative of phosphonic acid. This drug can have a bactericidal effect, which is explained by the suppression of the synthesis of bacterial cell walls.
Being an analog of phosphoenolpyruvate, actingthe substance interacts with the enzyme N-acetyl-glucosamino-3-o-enolpyruvil-transferase. As a result, its irreversible, selective and specific inhibition occurs, which ensures the absence of cross-resistance with other antibiotics, as well as the possibility of synergy with them.
Monural is active against manygram-positive bacteria and most gram-negative microorganisms. Its active substance reduces the adhesion of bacteria on the epithelial layer of the urinary tract.
How long does the "Monural" act? The active substance of the drug almost immediately after administration is absorbed from the gastrointestinal tract. At the same time, it quickly accumulates in the urine.
При однократном применении лекарственного solution its bioavailability is 35-65%. The active substance of the drug does not bind to plasma proteins, but in the human body it dissociates into trometamol and fosfomycin and is no longer metabolized.
When receiving a single dose of "Monural" in the amount of 3 g, its concentration in the urine reaches a high level (99%) of bactericidal action against many pathogens of urinary tract infections.
So how many hours does Monural help?According to the attached instructions, its maximum concentration is reached in approximately 120-160 minutes. After this period of time, the drug begins its active action.
Displays the drug in unchanged form (about 95%) through the kidneys. At the same time in urine its highest concentrations are noted. Also 5% of the active substance is excreted along with the bile.
The half-life of the antibiotic is four hours.
How much time will Monural help patients?with a moderate decrease in renal function? In this category of people, the effect of the drug is also noted after two hours. It is during this period that the drug reaches high concentrations in the blood. However, in these patients, the half-life of fosfomycin from plasma is slightly increased.
How much does Monural help with cystitis? Two days is enough for the patient to develop a lasting therapeutic effect.
As mentioned above, this medicine is used to treat various diseases of the urinary system. In particular, this drug helps with:
It should also be noted that the solution fororal administration is often used as a prophylactic against urinary tract infections in the process of diagnostic transurethral studies and in surgical intervention.
As evidenced by the available onwe have a pharmaceutical industry product (Monural medicine) reviews, in case of cystitis, its action is quite effective. However, do not forget that any medication has contraindications. According to the instructions, this drug is not recommended when:
With cystitis, as well as other diseasesurinary system content of one sachet must be dissolved in 1/3 cup of ordinary water. The resulting solution should be taken 2 hours before meals or 120 minutes after. It is not recommended to use the drug in the process of food intake, as this will significantly slow down its absorption in the body.
According to the instructions, take the considered drug preferably at night. This should be done after emptying the bladder.
For one course of treatment, one sachet withdrug. It should be noted that it is prohibited to combine "Monural" with a drug such as "Metoclopramide". This is due to the fact that the combination of these funds can significantly reduce the concentration of fosfomycin in the blood and urine. As a result, you will not achieve the effect of therapy.
Людям, которые страдают от сахарного диабета, it is necessary to take into account that sucrose is part of the “Monural” drug. It should also be noted that during its reception it is forbidden to consume any alcoholic beverages.
"Monural" with cystitis (contraindications andthe use of the drug has been described above), as well as for other diseases, adults should be taken in a dosage of 3 g (once a day). When this solution is used once.
If necessary, the attending physician may prescribe his patient to take the drug again, but only after a day has passed.
As a rule, such therapy is required whenrecurrent bacterial infection, severe course of the disease (for example, in the absence of proper results after a single dose of the drug), as well as in old age.
Для профилактики различных инфекций мочевыводящих pathways for urological intervention or diagnosis of this medication is also prescribed twice. The solution is taken three hours before the planned manipulation or any medical research. The interval after the first dose should be 24 hours.
People with renal insufficiency should receive the drug "Monural" with extreme caution. Such patients need to increase the time between taking the medicine or reduce the dose.
Данный медикамент можно назначать детям, но лишь those who have reached the age of 5. The drug is recommended for babies to be taken once in an amount of 2 grams. A child until the specified age “Monural” is not prescribed due to an unformed renal pelvic system (that is, the kid has not yet developed a filtration system in the kidneys).
During pregnancy, women often suffer from cystitis. Monural solution effectively treats this disease and does not cause pathology in the fetus.
Самым большим плюсом данного препарата является taking it once, while most antibiotics are required to take at least 5-7 days. It should also be noted that this medicine has virtually no side effects and contraindications. As a rule, it is well tolerated by patients. However, only an experienced doctor can prescribe this remedy to pregnant women after a thorough examination. Indeed, many experts know that the active substance "Monural" easily overcomes the placental barrier. Therefore, in the first trimester of pregnancy, its reception is extremely undesirable.
As for lactation, during this periodThe preparation in question is generally prohibited. If there is an urgent need to take it, breastfeeding should be discontinued, since fosfomycin enters the milk.
The drug "Monural" for the treatment of cystitis is best suited. Specialists have proven that this drug is effective against many bacteria that cause this disease.
Besides the fact that the agent has bactericidal properties, it also noticeably reduces the ability of microorganisms to adhere to the walls of the bladder.
Treatment of acute cystitis should begin immediately. This is necessary in order to prevent the disease from becoming chronic.
As for the exacerbation of chronic cystitis, the antibiotic should be taken on the first day. The solution is used once at the dose indicated above.
There are many reviews about this drug, as "Monural". Most patients leave only positive comments about him, although occasionally negative responses can be found.
So, according to reviews, the positive sideThis drug is its high efficiency - the result is observed after a single dose of the solution. However, it almost never causes any side effects.
The process of treatment with this agent is called convenient by many patients, and its cost is quite acceptable.
Negative reviews indicate thatThis medicine is ineffective. But at the same time, patients do not say under what indications and when Monural was taken, whether the dosage was observed, the doctor prescribed it, or the patient self-medicated.
