The medicine "Enam" instructions for usecharacterizes as an inhibitor (reducing activity) angiotensin-converting enzyme. The active ingredient is enalapril maleate. The drug is available in tablet form.
The preparation "Enam" carries out a gradualdecrease in diastolic and systolic pressure, practically without affecting the frequency of heart contraction. The drug helps to increase renal blood flow, improve kidney function, prevents the development of diabetic nephropathy. As studies show, the systematic use of the Enam drug reduces mortality on the background of heart failure. The drug has no effect on lipid and carbohydrate metabolism.
Medication Enam. Application
The medicine is prescribed for arterial hypertension. The drug as part of complex therapy is recommended for chronic heart failure.
Means Enam. Instructions for use
Dosage and duration of therapy is determined by the attending physician.
As a rule, with arterial hypertensionthe initial dose is five milligrams a day. Take the medicine should be one time. If necessary (on the recommendation of the doctor), the dosage may be increased to ten or twenty, and in some cases up to forty milligrams per day. The amount of the medicine can be taken once or divided twice. With the simultaneous use of diuretics, the dosage of the Enam medication is reduced to two and a half milligrams per day.
Patients with congestive heart failure,as a rule, appoint 2.5 mg per day once or twice. An increase in the dosage of Enam's medication is recommended by the application instruction gradually. As maintenance therapy, usually five to twenty milligrams a day is prescribed.
To side effects when using a medicine"Enam" instructions for use include a disorder of taste, tinnitus, angioedema, rashes, dry cough. The drug can provoke muscle cramps, orthostatic reactions, diarrhea, drowsiness, nausea, fatigue. Continuous use of the Enam drug may cause an increase in the urea index, agranulocytosis, leukopenia, impaired renal activity, thrombocytopenia, pancreatitis. Negative reactions include vasculitis, myalgia, vision disorders, impotence, alopecia, anorexia.
The medicine "Enam" does not allow the instruction toadministration to persons with hypersensitivity to enalapril or the product of its disintegration (enalaprilat), anginaurotic edema (in anamnesis), porphyria. Contraindicated in lactation and during pregnancy. Due to the lack of information on the effectiveness and safety of using the drug in childhood, the drug is not prescribed for children.
In case of overdose, pronounced hypotension is noted with violation of perfusion (blood passage) in vital organs.
To facilitate the condition, the patient should be transferred to a horizontal position, and a gastric lavage should be performed. Activated charcoal is assigned. Symptomatic therapy is indicated.
special instructions
The medicine "Enam" can provoke a pronounced hypotension, especially when first used by patients with kidney and heart failure of chronic course and hyponatremia.
To prevent the development of hypotension beforeprescribing the drug for two or three days is recommended to suspend the intake of diuretic medicines and salt-free diet. If it is not possible to implement these recommendations, the Enam is prescribed in a minimum dosage of two and a half milligrams.
Before using the medication, read the notes carefully.
