Средство "Фентанил" инструкция по применению defines as an analgesic drug that increases the threshold of pain susceptibility and increases the activity of the antinociceptive system. The drug excites opiate receptors of the central nervous system, peripheral tissues and spinal cord, as well as disrupts transmission of excitation to the amygdala complex, nuclei of the hypothalamus and thalamus. The use of the drug "Fentanyl" (instruction for use confirms this) provides a pronounced hypnotic effect, allows you to change the emotional color of the pain syndrome, reduce intestinal peristalsis and increase the muscle tone of the sphincter and biliary tract. In addition, this analgesic agent reduces renal blood flow, excites the vomiting center and depresses the respiratory.
Выпускается препарат "Фентанил", цена на который is between three and seven thousand rubles, mainly in the form of a solution for intramuscular and intravenous injections. There are also patches with this name on sale. Use the product manufacturer recommends as an introductory anesthesia (in conjunction with nitrous oxide or droperidol) before all sorts of surgical interventions. In addition, the drug "Fentanyl" can be used for chronic pain in cancer and severe pain syndrome of various etiologies. In addition, this analgesic medicine is allowed to be used as a component of balanced anesthesia. Neuroleptanalgesia and postoperative analgesia are also indications for the administration of this solution.
Use the drug "Fentanyl"the instructions for use categorically prohibit if the patient has bronchial asthma, hypersensitivity or high intracranial pressure.
Pregnancy is also included in the list of directcontraindications. It is not necessary to appoint this remedy in painful conditions, which are accompanied by a pronounced depression of the respiratory center, and with caesarean section. Contraindications are also the lactation period and dependence on narcotic drugs.
If we consider possible side reactions,which can provoke the drug "Fentanyl", then in the first place should be allocated a rather high risk of respiratory depression (in the case of using large doses, a complete stop is possible). In addition, the manufacturer notes the possibility of short-term muscle stiffness, urinary retention and bradycardia. Bronchospasm, hypoventilation, hallucinations and confusion may also occur due to the use of the analgesic agent "Fentanyl". Instructions for use notes and the risk of a variety of local skin reactions - rash, itching, erythema. In addition, some groups of patients may experience paradoxical stimulation of the central nervous system, amblyopia, hepatic colic, constipation, nausea, or vomiting.
