Discovery of antibacterial action of moldsfungi, from which penicillin was made, became a real revolution in medicine. But over time, the pathogenic microflora has adapted to the action of this drug. This forced the scientists to develop synthetic analogues of penicillin, one of which was "Flemoxin Solutab". Instruction, description of the drug will help to avoid its negative effects on the body and side effects.
В состав одной таблетки "Флемоксина" входит acid-fast amoxicillin in the form of amoxicillin trihydrate at 125, 250, 500 and 1000 milligrams. This substance has a strong bactericidal effect. Also, drugs with amoxicillin are used against gram-positive and gram-negative bacteria. Sometimes it is used to fight the pathogens of intestinal infections. But in the latter case it is less effective.
In the preparation of the preparation, auxiliary substances were used, such as single-crystal cellulose, vanillin, dispersible cellulose, magnesium stearate, crospovidone, saccharin, flavors.
The drug is intended for systemic use and is a broad-spectrum medicine.
How does the "Flemoxin Solutab"(Flemoxin Solutab)? The instruction says that after taking the active ingredient of the drug - amoxicillin - almost all are absorbed in the shortest time (almost 93 percent). And the absorption of the drug is not related to the ingestion of food.
In plasma, the maximum amount of the drugis found one or two hours after administration. After getting into the digestive tract of the drug "Flemoxin Solutab 500 mg" (the instruction for use confirms this), the maximum concentration of amoxicillin is noted in researchers after 2 hours. This maximum is 5 μg / ml. If, for any reason, the dose of the medicine decreases or increases, then its concentration, respectively, decreases or increases.
Twenty percent of the substance binds toplasma proteins. The therapeutic effect is achieved almost always, since the drug perfectly penetrates into the intraocular fluid, bones, mucous membranes, sputum. In the bile, amoxicillin falls in two or even four times more than in the plasma. In the umbilical cord and amniotic substance, twenty-five to thirty percent of the flemoxin is found from its concentration in the blood of the pregnant woman.
Bad penetration of the active substance through the blood-brain barrier was noted: in the cerebrospinal fluid, its quantity does not exceed twenty percent when used.
The drug is excreted by the kidneys.Eighty percent of the active substance is processed by tubular excretion, the remaining twenty are filtered by glomeruli. Healthy kidneys half amoxicillin an hour and a half. In children up to six months, the elimination half-life is between three and four hours. Dysfunction in the liver does not affect the half-life of the drug.
"Flemoxin Solutab" (table 500 mg 20 pcs., as well as other dosages of the drug) is an acid-fast bactericidal antibacterial agent with a wide spectrum of action. They refer it to a group of semisynthetic penicillins.
It has a harmful effect on many gram-negativeand Gram-positive microorganisms, such as most varieties of streptococci, clostridia, staphylococci, helicobacteria, coliculus eserichia, proteins, salmonella, cholera vibrio.
"Flemoxin Solutab" (Table.500mg n20), the instruction confirms this, it has not only advantages, it also has its contra-indications. This is also true for other dosages of the drug. The drug is not prescribed or prescribed with great care in such cases:
Infectious ailments of the stomach, intestines and biliary tractways, as well as gynecological diseases of an infectious nature, are treated three times a day in a dosage from one and a half to two grams or four meals a gram and a half at a time.
Adult people with leptospirosis are treated with a four-fold "Flemoxin Solutaba" solution at 0.5-0.7 grams. Treatment should last from six to twelve days.
Carrying salmonella requires a three-fold application of one and a half to two grams for two to four weeks.
To avoid endocarditis with smallsurgical interventions, prescribe three to four grams of the drug an hour before the operation. If there is a need for repeated use of the drug, it is prescribed after eight to nine hours in the same dosage.
If the kidney is broken, the interval betweenshould be up to 12 hours. For more serious disorders, reduce the dose. If the patient has anuria, the maximum dose should not exceed two grams.
Newborn and premature children are reducedor increase the gap between doses. For prophylaxis of endocarditis with small surgical operations, an hour before the procedure is prescribed from one and a half to two grams. If necessary, re-appoint eight to nine hours after surgery.
Whatever medicine is ideal, from whatever natural components it is created, there are risks of side effects that can affect a patient's condition.
This drug patients are evaluated as veryeffective and relatively safe. It is bioavailable, so the effect from it is very quickly manifested. After the start of treatment, the condition of adults and children improves during the first 24 hours. Depending on the dosage and destination, "Flemoxin Solutab" is very quickly absorbed into the blood. Its action lasts for eight hours. In this case, the concentration of the substance is noted 15 minutes after use.
As experts note, for children this antibiotic is one of the safest. It is used from early childhood on the prescription of a doctor.
Этот препарат имеет множество синонимов, то есть medicines that are made on the basis of amoxicillin. But there are also some medicines with another active substance, but they are used with the same health problems as Flemoxin Solutab. Such preparations are called analogues of the above. The active substances in them are also antibiotics, semisynthetic penicillins. They are used for sepsis, abscesses, infections of the ENT organs and respiratory tract, urinary tract, skin, GI tract, soft tissues and so on.
Such analogues of the drug include:
Аналоги препарата, особенно антибиотика, it is necessary to discuss with the attending physician. This is very important, because the dosage, the nature of treatment and duration is determined only by a specialist. Also, he knows better what kind of active substance is appropriate in a particular case.
If treatment with a drug is carried out in courses, the kidneys, liver, hematopoiesis should be monitored.
If the patient is sensitive to the penicillin group, there may be cross-allergic manifestations.
If during the treatment there was a slight diarrhea,You should avoid drugs that reduce intestinal peristalsis. If there is severe diarrhea, you should seek medical advice from a medical institution. After the disappearance of clinical manifestations, it is recommended to take Flemoxin Solutab for another three to four days.
The drug can reduce the contraceptive effectfrom oral contraceptives, therefore during its reception it is necessary to take care of additional contraception. It also does not work well with aminoglycosides, indirect anticoagulants, methotrexate, digoxin, alopurinol, diuretics, oxyphenbutazone.
Before using it is important to familiarize yourself with the features of the use of the drug Flemoxin Solutab. Instructions for use, reviews will help to avoid undesirable consequences.
Drug prices in different citiesfluctuate from 176 rubles (in Nizhny Novgorod) and up to 228 rubles (in Novosibirsk). In the capital, "Flemoxin Solutab" can be purchased at a price of 191 rubles. In St. Petersburg, it costs an average of 184 rubles.
Do not forget that the instruction for the use of the drug "Flemoxin Solutab" is mainly made for the doctor. And only he can prescribe or cancel a drug. Avoid self-treatment!
