The drug "Tulip" includes a componentatorvastatin. This substance is a competitive selective enzyme inhibitor that participates in the conversion of 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate (the precursor of cholesterol and other steroids). Atorvastatin helps lower the synthesis and concentration of LDL and total cholesterol, apolipoprotein B in patients with mixed hyperlipidemia , hypercholesterolemia (primary, heterozygous and homozygous familial). When ingested, there is a high absorption of the component. The concentration of atorvastatin reaches a maximum after an hour or two. When eating, the absorption decreases slightly. The degree of absorption is dose-dependent. Metabolism occurs in the cells of the liver.
The drug "Tulip". Instructions for use
Before starting therapy, the patient should bea diet with a lowered level of cholesterol is prescribed. The drug is taken orally, regardless of food. Dosage - from 10 to 80 mg once a day. With primary hypercholesterolemia and mixed hyperlipidemia, they are prescribed ten milligrams once a day. Subsequently, the amount of the drug increases in accordance with the target cholesterol content and the response of the patient's body. After 2-4 weeks from the beginning of therapy, a determination of the lipid concentration is carried out. In accordance with the result of the verification, a further reception circuit is corrected. The maximum amount of medication per day is 80 milligrams. For patients with kidney failure, dose adjustment is not required.
The drug "Tulip". Instructions. Contraindications
Do not prescribe medication in active stagespathologies of the liver: chronic hepatitis, alcoholic including liver failure, increased activity of AST and ALT (more than three times higher than the upper level of the norm). It is not recommended for women of reproductive age who do not use adequate contraceptives. Contraindications include intolerance to the components of the drug, pregnancy. The drug "Tulip" instructions for use do not recommend during breastfeeding. Caution is shown with patients who abuse alcohol, have disorders in the electrolyte balance, metabolic and endocrine disruptions, arterial hypertension. Dose adjustment may be required against a background of pathologies in skeletal muscles, with uncontrolled epilepsy, in acute severe infections (sepsis, for example). Efficacy and safety are not established even when taking medication by children.
The drug "Tulip". Instructions for use. Adverse Reactions
During treatment, constipation may occur,pancreatitis, glossitis, dysphagia, vomiting. Negative manifestations include: nosebleeds, dry mouth, anorexia, changes in appetite, tenesmus. When taking the medication, sometimes there are ataxia, headache, insomnia, cholestatic jaundice, peptic ulcer, belching, lesions in the oral cavity of erosive ulcerative character.
The drug "Tulip". Instructions for use. Price
The cost of the medicine is from 200 rubles in pharmacies.
