Ointment "Lokoid" is used in the treatmentsuch diseases as psoriasis, as well as unspecified, atopic and contact dermatitis. The main active substance in this medicine is hydrocortisone 17-butyrate, as a base is used vaseline oil, ointment is used as an external agent. Ointment "Lokoid" is produced in aluminum tubes, which also have an aluminum membrane. It has a uniform shape, oily to the touch, translucent, the color can be from white to light gray.
Ointment "Lokoid" is characterized by localanti-inflammatory, as well as antipruritic and decongestants. After applying the ointment to the body, the active substance gradually accumulates in the upper layers of the skin, namely in the epidermis, the systemic absorption of this ointment is insignificant. There is also absorption of a small amount of hydrocortisone 17-butyrate in the systemic blood stream in unchanged form.
Ointment "Lokoid", or rather its active substancehydrocortisone 17-butyrate, is metabolized to hydrocortisone, as well as other metabolites, directly into the epidermis and only after that in the liver. The metabolites formed and also part of the unchanged active substance are excreted through the intestine and kidneys.
"Lokoid" ointment - use
If you apply ointment in recommendedthe hypothalamic-pituitary-adrenal system is not suppressed. Incorrect use of the drug or its use in large quantities and a long period of time, even under occlusive dressings, gradually leads to an increase in the amount of cortisol in the blood plasma, but very rarely causes a decrease in the reactivity of the pituitary-adrenal system. After the abolition of the use of this drug, everything quickly returns to normal.
A lokoid is used for various superficial uninfected skin diseases. These include such types of dermatitis as seborrheic, contact, atopic; eczema and psoriasis.
Contraindications to the use of this drug
All cases when the human bodyhypersensitive to hydrocortisone or other components of the drug, as well as in the presence of bacterial skin infections, for example, gram-negative follicle, strepto- and staphyloderma and others. Also, the use of the drug is not allowed in the presence of human viral, fungal and parasitic skin infections, tuberculosis lesions, as well as syphilitic skin lesions, any tumors and in the post-vaccination period. Care should be taken if the patient has a sick wound or ulcers and is not recommended for women during pregnancy and lactation. In pregnancy, GCS penetrates the fetus through the placenta, especially this is pronounced when treating large areas of the skin.
Side effects
They can be expressed in irritation of the skininteguments. If the drug is taken for a long time, then side effects may appear, which are typical for all systemic SCSs. The use of lokoid causes much less side effects than the use of fluorinated steroids. Currently, there is no evidence of an overdose of this drug.
Apply the drug to the affected skin before3 times a day with a thin layer, in order for the drug to function better, it is necessary to perform massaging movements when applying it. For a week, do not use more than 60 grams of the drug.
Do not apply the drug around the eyes,so as not to provoke the development of glaucoma, and with its constant contact with the conjunctiva, intraocular pressure may increase. On the scalp of the body, for example on the head, in the genital area it is better to use the cream "Lokoid".
"Lokoid" ointment, analogues of which "Lokoid Krelo" and"Lokoid Lipokrem" also have a rapid anti-edematous, anti-inflammatory, antipruritic effect, but have a softer effect, sold without a doctor's prescription.
