Do you know about what helps thisa drug like Losek MAPS? Instructions for use, as well as the indications of this medication will be described in this article. In addition, we will tell you about how much this means is worth, whether it has analogues and contraindications, what side effects occur after taking and so on.
What is the drug "Losek MAPS"?Instruction for use informs us that this preparation is available only in the form of tablets. The active ingredient of the medication is omeprazole (10, 40 or 20 mg). The tablets also include auxiliary components: glyceryl monostearate, MCC, hydroxypropylmethylcellulose, hydroxypropyl cellulose, magnesium stearate, sugar, methacrylic acid copolymer, talc, paraffin, triethyl citrate, polyethylene glycol, titanium dioxide, polysorbate, iron oxide, crosslinked polyvinylpyrrolidone and sodium stearyl fumarate .
You can buy medication in bottles of 14, 7 or 28 tablets (10, 40 or 20 mg), placed in a cardboard box.
How does the drug "Losek MAPS" work?The instruction for use states that this drug is an inhibitor of H + -K + -ATPase. Moreover, it refers to antiulcer drugs. Its active substance is a weak base. It is concentrated in the acidic environment of parietal cells of the gastric mucosa by activating and inhibiting the proton pump.
The effect of omeprazole on the described process isdose-dependent. The drug is able to provide a highly effective inhibition of stimulated and basal secretion of hydrochloric acid regardless of the stimulating factor.
With a daily oral intake of medication"Losek MAPS", the price of which will be presented a little further, provides an effective and rapid inhibition of night and day secretion of hydrochloric acid. The greatest therapeutic effect is observed within 4 days of treatment. In people with a duodenal ulcer, 20 mg of the drug causes a steady decrease in the 24-hour gastric acidity by at least 80%. It should also be noted that this dose of the drug is able to maintain an acid level pH> 3 in the intragastric environment. This effect lasts for 17 hours.
How effective is it with respect tomentioned bacterium drug "Losek MAPS"? The instruction, applied to the drug, says that omeprazole has a high bactericidal effect on Helicobacter pylori. Eradication of this bacterium during the application of the drug in combination with antibacterial medicines is accompanied by a fairly rapid elimination of all symptoms, as well as a high degree of healing of the affected mucosa of the gastrointestinal tract. In addition, such treatment contributes to a long-term remission of peptic ulcer, which significantly reduces the likelihood of repeated bleeding.
What other properties does this drug have,as "Losek MAPS"? Experts say that patients who regularly and for a long time take drugs that reduce the secretion of the glands of the digestive tract, very often there are glandular cysts in the stomach. As a rule, they are benign and pass by themselves.
Lowering the secretion of acid hydrochloride in the stomach promotes normal intestinal microflora. However, this may lead to a slight increase in the risk of infection.
In adults and children who took this remedy for a long time, an increase in the number of enterochromaffin-like cells is observed.
During treatment with omeprazole, the concentration of gastrin in the blood slightly increases.
Is the drug "Losek MAPS" absorbed into the bloodstream?Instructions for use asserts that the absorption of omeprazole occurs in the small intestine (for 4-6 hours). Eating food for bioavailability of this substance is not affected. After oral administration, it is about 60%.
The drug is completely metabolized in the liver.The half-life is about 30-80 minutes. Approximately 80% of the active substance is excreted as metabolites by the kidneys, and the remainder along with the feces.
Tablets "Losek MAPS" appoint at the following deviations:
The drug "Losek MAPS" can not be prescribed for hypersensitivity of the patient to omeprazole, as well as substituted benzimidazoles or other ingredients that are part of the drug.
Также следует отметить, что данный медикамент с caution is prescribed to people in the presence of such symptoms as spontaneous weight loss, dysphagia, frequent vomiting and vomiting with blood. In addition, with a stomach ulcer (or suspected of a disease), it is necessary to exclude the presence of a malignant tumor. This is due to the fact that treatment with omeprazole can easily disguise the symptoms of the disease and delay the setting of the correct diagnosis.
The agent should be taken only by mouth in the morning. The medicine must be swallowed whole, washed down with water. The drug can not be broken or chewed.
Tablets are allowed to dissolve in slightly acidified liquid or water, (for example, in fruit juices). However, the resulting solution should be drunk within half an hour.
With esophageal reflux, stomach ulcer, as well as 12 duodenum, the drug is prescribed 20 mg once daily. With reflux-esophagitis, the dose is doubled.
The duration of treatment for ulcers is2-4 weeks, with reflux-esophagitis - 4 weeks, and gastroesophageal reflux - 4-8 weeks. To prevent recurrences of ulcers and reflux esophagitis, a longer duration of 10 mg dose may be prescribed.
The drug "Losek MAPS", analogues of the drug maycause side effects. The most frequent are the following pathological conditions: headache, flatulence, abdominal pain, constipation, diarrhea, nausea and vomiting.
To infrequent side effects include: dermatitis, hives, dizziness, itching, paresthesia, rash, malaise, drowsiness, increased activity of liver enzymes and insomnia.
Rarely in patients takingomeprazole, hypersensitivity reactions (eg, anaphylactic shock, fever, anaphylactic reaction, angioedema), as well as bronchospasm, hepatitis, muscle weakness, hepatic insufficiency, leukopenia, encephalopathy, arthralgia, depression, myalgia, pancytopenia, thrombocytopenia, agitation, agranulocytosis, dry mouth, hyponatremia, candidiasis of the digestive tract, aggression, photosensitivity, confusion, blurred vision, hallucinations, sweating, taste disorder, peripheral edema, stomatitis, interstitial nephritis, alopecia, gynecomastia, erythema multiforme, microscopic colitis, Stevens-Johnson syndrome and epidermal toxic necrolysis.
Very rarely observed hypocalcemia, hypomagnesemia, hypokalemia and hypomagnesemia.
Compared with similar drugs, the pricethe means under consideration is quite high. So, for 14 tablets you have to give about 250 Russian rubles. Given the long-term use of the medication (2 to 8 weeks), treatment is too expensive for them.
What is the substitute for the drug "Losek MAPS"? Analogues of this tool have the same efficiency. However, before using them, you should always consult a doctor.
So, you can replace the drug "Losek MAPS" withwith the following medications: Omeprazol-Acry, Vero-Omeprazole, Cisagast, Gastrozol, Helol, Demeprazole, Helicid, Zhelkizol, Ultop, Zerocid, Ulkozol , "Zolser", "Ulzol", "Krismel", "Sopral", "Losek", "Romesque", "Omez", "Promez", "Omez D", "Pleom-20", "Omez Insta" Pepticum, Omezol, Ozid, Omekaps, Ortanol, Omeprazol, Omitox, Omeprazol-Richter, Omipix, Omeprazol Stada, Omizak, Omeprazol Zentiva , Omefez, Omeprazol Sandoz, Omeprus, Omeprazol-OBL, Omeprazol-FPO, Omeprazol-Teva, Omeprazol-AKOS.
What do patients say about the drug "Losek MAPS"?Reviews about this tool are extremely positive. According to those who have ever taken this medication, it quite effectively eliminates all the symptoms of increased acidity of gastric juice. And the result is noticeable almost immediately after taking the tablets (after 1-2 hours).
Often, the remedy is used for heartburn and a burning sensation behind the sternum.
Despite the high effectiveness of the drug,most patients complain that after the cessation of its reception, unpleasant sensations come back. In this case, doctors recommend a comprehensive treatment and use the medication for at least four weeks.
