The drug "Cefixim", analogues of the agent (for example,medicament "Maksibat"), are third-generation cephalosporin antibiotics that have bactericidal action (capable of disrupting synthesis in the bacterial cell wall). Medicines have an effect on different anaerobic and aerobic microorganisms, both gram-negative and gram-positive.
Biological availability of the drug at admissionthe inside is 45%. The drug binds to proteins in blood plasma at sixty five percent. Excretion is performed by 50% kidneys in an unchanged form. 10% are excreted with bile. The drug in high concentrations is stored in urine, bile and serum for an extended period.
The drug "Cefixim" recommends the use ofinfections of bacterial nature in the lower and upper respiratory tract: bronchitis, tonsillitis, sinusitis, pharyngitis. The medication is indicated for infectious pathologies of bile ducts, soft tissues, urinary system, skin, with average otitis, uncomplicated gonorrhea in the cervix and urethra, endometritis, osteomyelitis and other diseases associated with the vital activity of drug-sensitive microbes.
The drug "Cefixim" instruction prohibitsappointment to children up to six months, pregnant and lactating patients, patients with hypersensitivity to components. Particular care is taken when taking the drug in the elderly, with the presence of colitis (in the history of the disease, including).
Cefixime remedy for userecommends taking internally. The daily dose of medication for patients from the age of twelve (with a body weight of more than fifty kilograms) is four hundred milligrams a day or two hundred milligrams twice a day.
With a patient's weight less than the specified, prescribe a medicine in a dose of three to nine milligrams per kilogram. Subsequently, the dosage can be increased to 12 mg / kg.
The duration of the drug "Cefixim" on average seven or ten days.
To eliminate uncomplicated gonorrhea in the cervix and urethra, four hundred milligrams are prescribed once.
Children up to the age of twelve are prescribed a medicine insuspended form. Dosage of the drug "Cefixim" instruction recommends the following: up to a year - 2.5-4 ml, from two to four years - 5 ml, from five to eleven years - 6-10 ml. Assign the medication every twelve hours.
To prepare the suspension, adda bottle of powder forty milliliters of boiled water (in two stages) and shake to form a homogeneous (homogeneous) mixture. The suspensions are then allowed to stand for five minutes. Before using the medicine, the vial should be shaken.
The most common unwantedmanifestations when taking the drug "Cefixim" instructions include tinnitus, fever, itching, dyspnoea, skin flushing, hives, dizziness, eosinophilia, and leukopenia. In some cases, thrombocytopenia, neutropenia, dysbacteriosis, hemolytic anemia, candidomycosis may occur. Side effects include nausea, headache, diarrhea, stomatitis, hypovitaminosis B. The drug "Cefixim" can provoke interstitial nephritis, vomiting, pseudomembranous colitis.
Patients with a history of illnessinformation on allergic reactions to penicillins, probably the manifestation of hypersensitivity to antibiotics from the cephaplosporin series. During the therapeutic course, the development of a false positive direct reaction of Coombs and urine to glucose is possible.
Before the beginning of treatment it is necessary to conduct all necessary tests, to undergo examination. Before using the drug "Cefixim" you should read the instructions for use.
