/ Invasive breast cancer: causes, diagnosis, treatment. Blood for tumor markers

Invasive breast cancer: causes, diagnosis, treatment. Blood on oncomarkers

Breast cancer is not associated with age,social belonging or gender. Pathology can appear in every person. However, in percentage terms, the proportion of men among the sick is negligible. There are different forms of breast cancer. In this article, we will dwell in more detail on the invasive pathology.

The structure of the female breast

To better understand the pathogenesis of the disease, it is necessary to understand the anatomy of the breast. In its structure it is customary to distinguish the following parts:

  • fat;
  • connective tissue;
  • mammary gland;
  • ducts;
  • lobules of mammary glands.

Another important part of the breast is lymphadenitis. They catch cancerous elements and harmful microorganisms, performing a protective function.

Pregnancy promotes a strengthenedproduction of milk in the glands. Then it flows from the nipples along the ducts. Certain types of malignant neoplasms of the gland begin their development, affecting several thoracic ducts. Among them is invasive cancer.

invasive breast cancer

Description of the disease

Invasive breast cancer is seriousoncological disease. It is characterized by the spread of a tumor in adipose or connective tissue. By invasion is meant the ability of malignant elements to isolate themselves from the primary focus and quickly infect the surrounding organs. This is one of the conditions for tumor metastasis. The treatment tactics depends on the invasiveness or non-invasiveness of the neoplasm.

In this disease, cancer cells rapidlyaffect nearby lymph nodes. In advanced stages, their activity spreads to the spinal cord, liver, and kidneys. If malignant elements are found outside the mammary glands, this type of pathology is called metastatic breast cancer.

invasive ductal carcinoma

Main reasons

Invasive breast cancer progresses slowly. It may be preceded by pretumor diseases, such as mastopathy. Let us consider in more detail the main causes of pathology.

  1. Mastopathy.The disease develops against the background of an imbalance of hormones in the body. Most often diagnosed in women under 40 years. For mastopathy is characterized by severe pain, discharge from the nipples. Tumor-shaped nodules form in the chest, leading to changes in the tissues of the organ and cancer.
  2. Fibroadenomas.This pathology mainly develops in young girls. Nodular formations of benign character appear in the chest. As a result of injuries, lack of treatment or hormonal failure, they begin to grow in size, affecting healthy tissue.
  3. Abortions. Surgical manipulations not only interrupt pregnancy, but can provoke the reverse development of glandular tissues. As a result, seals form, from which cancer develops.
  4. Lactation. Breastfeeding rejection is another cause of invasive cancer.
  5. Lack of intimacy. Irregular sexual life violates the hormonal balance in the body, which negatively affects the state of the mammary glands.

invasive breast cancer prognosis

Clinical manifestations of the disease

No one can be immune to breast cancer.According to statistics, every ninth of the fair sex suffers from the manifestations of this disease. According to doctors, patients can be several times more. More than a million women are unaware of the presence of a tumor. In the early stages, the pathology is almost asymptomatic, and it can only be diagnosed with the help of a comprehensive examination. Unfortunately, the appearance of the first signs often means that the disease has moved to a new stage of development. What symptoms indicate invasive breast cancer?

  • Discoloration of the skin of the nipple.
  • The appearance of a small seal or bumps in the chest.
  • Change in the size and shape of the mammary gland.
  • Bloody nipple discharge, burning sensation and discomfort.

If these symptoms are present, you should immediately consult a doctor to identify the causes.

female breast structure

Forms of the disease

The medical literature describes several pathology variants, which are invasive breast cancer. These diseases include:

  • Preinvasive cancer. The neoplasm does not spread to neighboring organs, but remains in the milky ducts.
  • Lobular cancer.The disease is diagnosed extremely rarely (in 15% of cases). The neoplasm develops in the lobules and ducts of the glands, can metastasize to adjacent tissues. The main symptom of pathology is chest pain during palpation.
  • Инвазивный протоковый рак.The neoplasm is formed in the milky ducts. Malignant cells gradually multiply in adipose tissue, but quickly metastasize to other organs. Ductal carcinoma is considered the most common form of invasive breast damage (about 80% of cases among all cancers).

Diagnostic Methods

Diagnosis of the disease usually begins withself-examination. The structure of the female breast allows to identify seals during palpation. Skin changes, nipple shape, and other symptoms indicating the severity of the pathology can also be detected independently. If you suspect a disease, you must consult a doctor. The specialist should conduct a physical examination and appoint an additional examination. Usually for diagnosis use mammography, breast ultrasound and MRI. When neoplasms are detected, a biopsy is performed. The obtained samples are then sent for analysis to the laboratory. The results of the study allow to determine the hormonal status of the tumor, its features.

 blood for tumor markers

Separately, you should tell about when and whydonate blood for tumor markers. This analysis is used to diagnose the disease, and then - to monitor the treatment. Oncomarkers are macromolecules that are synthesized in a woman’s body in response to the activity of cancer elements. When their level exceeds the norm, we can talk about the presence of a pathological process, but not always. In some cases, an increase in the number of macromolecules in the blood indicates an allergy, benign growth, or inflammation. If invasive cancer is suspected, the concentration of the following tumor markers should be checked: CA 15-3, CA 27-29, HER2. To obtain reliable results on the eve of the tests should relax, do not take alcohol. Blood for tumor markers is taken from a vein. Decoding the results involved a doctor in the laboratory.

Treatment options

There are several methods of dealing with invasivecancer: surgery, chemotherapy and radiation, biological, hormonal therapy. Commonly used complex treatment. First, the doctor removes the tumor. Then the patient is prescribed radiation therapy. It allows you to increase the effectiveness of the treatment by 70%. Irradiation is necessarily indicated to patients in whom the tumor size exceeds 5 cm. Chemotherapy, hormone therapy and biological therapy are used as systemic methods of cancer control. If progesterone or estrogen receptors are detected in the gland tissues, hormone treatment is used. In the absence of these elements, chemotherapy is prescribed.

invasive breast cancer grade 2

Prognosis for recovery

The prognosis for this disease depends onresults of the treatment. Invasive damage to the mammary glands is characterized by a high percentage of deaths. Therefore, in many states they are beginning to introduce screening programs that allow detecting oncology at early stages. There are four of them. Invasive breast cancer grade 2 or 1st, diagnosed in a timely manner, in 90% of cases ends with recovery. Positive dynamics is possible only with proper treatment. Survival rate in oncology of the 3rd degree is 47%, and in the 4th case - about 16%. In the later stages, invasive breast cancer is difficult to treat. The prognosis worsens significantly with the appearance of metastases.

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