Uncontrolled intake of various medicinaldrugs, especially antibiotics, as well as errors in nutrition lead to the fact that the body has increased the growth of pathogenic microflora. This process inevitably ends with the appearance of various diseases, one of which is the well-known thrush.
This problem causes a lot of trouble"mistress", which manifests itself in the form of burning, itching, cheesy discharge from the vagina. Having come to the pharmacy to get rid of this scourge, it is quite easy to get confused in the range of antifungal agents that are dazzling on the shelves. In our article we will talk about one of these products, and the instructions for use of the drug Futsis will be considered in detail.
The manufacturer produces the drug in several forms:
Рассмотрим состав препарата.If we talk about tablets, then they contain the main active ingredient - fluconazole, the amount of which can vary depending on the weight of the tablet. They can be from 50 to 200 mg.
As an aid in tablet form include:
Инструкция по применению «Фуциса» в виде dispersible tablets contain information about the content of sodium saccharin as an auxiliary component, American ice cream flavoring DC129, as well as aerosil.
The drug in the form of a solution contains 200 mg of fluconazole, soluble in 100 ml of physiological sodium chloride solution.
Such a dosage form as a gel contains 5 mg of fluconazole as its main substance, and as additional components it contains:
What form of drug to choose for treatmentthrush should be determined by the doctor, taking into account the patient’s condition and the characteristics of his body. For example, in the mild form of the disease, it will be enough to use Futsis 50 for therapy, the instructions for use of which contain detailed information about the treatment regimen and possible contraindications.
Fucis belongs to the group of medicaldrugs that have a pronounced antifungal effect, and on a wide group of microorganisms. As a result of the penetration of the drug into the body, yeast cells lose their enzymatic activity. In the cells of the fungus, ergosterol biosynthesis is disturbed, which leads to the appearance of holes in the cell membrane, and this results in its death.
If the doctor prescribes Futsis, the instructions forthe use of tablets 150 mg from thrush recommends first to determine the sensitivity of the flora, since not in each case, such therapy may be effective.
Given that the half-life of the mainactive ingredient is more than a day, then it makes it possible to apply the medicine only once every 24 hours. Fluconazole is fairly well distributed throughout the body, its concentration in tissues and fluids is almost the same as in blood plasma.
Instructions for use "Futsisa" says that most of the medication is excreted by the kidneys.
This drug is used for various infectious diseases caused by fungi and having different localization. Most importantly, they should be sensitive to fluconazole.
If Futsis is chosen for treatment, the instructions for use of the 200 mg tablet contain information about the problems with which such treatment will be effective. The following diseases can be noted:
Instructions for use "Futsisa" claims thatThe drug is quite effective as preventing the spread of fungal infection in patients who have immunodeficiency or are undergoing cytokine therapy or radiation therapy.
"Fucis" in the form of a solution for injection is usually used for systemic fungal infections. This also includes all those diseases that were listed earlier.
Any drug hascontraindications to use, not an exception, and "Futsis" 200. Instructions for use warns that there are conditions in which therapy with this drug is undesirable:
Before proceeding with drug therapy, instructions for use "Futsisa" recommends that discuss this issue with your doctor.
Even if the patient has no contraindications touse of this drug, it does not mean that it will bypass the side effects during treatment. And they can be as follows:
All these manifestations do not depend on the dosage of the drug “Fucis”, the instruction on the use of the 150 mg tablet contains a list of the same side effects.
With what dosage of active ingredient to prescribe tablets and for how long - only the doctor determines the results of the survey. The dosage usually does not depend on the way the medication is used.
If you choose the drug "Futsis" 200 mg,Instructions for the use of drugs in different age groups pay great attention. It is allowed to use them in the treatment of adult patients, as well as children who have already turned 7 years old. Tablets are usually taken by mouth, they can be consumed at any time of the day and not coordinated with food intake. Most often, the entire recommended dose is taken once a day.
Now let us consider in more detail the dosage and treatment regimen for various diseases:
If older patients have kidneys worknormal, then dosage adjustment is not required for them. If there are problems with the kidneys, "Fucis" at the beginning of therapy is prescribed in a dosage of from 50 to 400 mg, and then, depending on the indicators of creatinine clearance.
It has already been repeatedly said that the drug canUse only in children older than 7 years. The dosage in each case is prescribed only by a doctor. It must be borne in mind that the daily dose should not be greater than that in adults.
If the child has candidal infectionsmucous membranes prescribe a drug at a rate of 3 mg per kilogram of weight 1 time per day. On the first day of treatment, the doctor may prescribe a single shock dose of 6 mg per 1 kg of body weight to achieve the maximum concentration of fluconazole in the body.
As a prophylactic agent "Futsis"can be assigned to a child at a rate of 3 to 12 mg per kilogram of weight. It must be remembered that the course of treatment can only be stopped when negative test results are obtained.
Dispersed Tablets Available"Futsis DT." Instructions for use advise before use to dissolve the pill in a teaspoon of water, if the tablet is 50 mg. In this form, the drug is approved for use by adults as well as babies from the age of three.
In the presence of candidal infection in the oralthe cavity will need to dissolve the drug in an amount of 50-100 mg in a small amount of water and rinse the oral cavity. Then the solution must be swallowed. This procedure must be done once a day for two weeks.
For other indications, the drug is prescribed according to generally accepted recommendations.
The instructions for use should be carefully studied by patients with reduced immunity to Futsis DT, tablets for such patients will have to take much longer.
If a woman is diagnosed with thrush, thenyou can use gel for treatment. It must be remembered that it is advisable to take therapy simultaneously with a partner. In 1 gram of the drug contains 5 mg of the main active substance.
Futsis gel is very convenient to use,the instruction for use recommends a single lubrication of the affected areas with the fungus. Before you spread the gel, you need to cleanse the skin. Numerous reviews confirm the effectiveness of the drug in this form, only the duration of therapy is slightly increased.
It is impossible to use “Futsis-gel” during pregnancy, the instructions for use with thrush allow it to be used only when the risk from such therapy is lower than the threat to the fetus.
The gel can also be used to treat oral candidiasis in young children. Just do not prescribe such therapy on your own, you need a specialist consultation.
If there is a need to use the drug"Futsis" in the form of a solution for infusion, for adults and children over 3 years of age, the dosage does not change. It is necessary to pay attention to the treatment regimen in babies. If administration to a newborn no older than 4 weeks is required, the drug is prescribed in the same doses as the older ones, but it is administered only once every three days. This is taking into account the fact that the elimination of the drug is much slower from the body.
From 4 weeks to three years, the medicine must be administeredin the same dosage, but once every two days. When treating babies with Futsis, it is necessary to carefully monitor the condition of the child and the manifestation of undesirable effects.
If you take the drug simultaneously with anticoagulants, then the effect of their use is enhanced, therefore, during such therapy, prothrombin time should be regularly monitored.
There is a risk of psychomotor reactions ifappoint "Futsis" at the same time as "Midazolam". Acceptance of the preparations "Benzodiazepine" and "Futsis DT" recommends that the instructions for use be carried out under the strict supervision of a doctor.
On the background of fluconazole therapy when taking“Cisapride” side effects are more pronounced, especially from the cardiovascular system. It is because of this that these two drugs are not prescribed at the same time.
It is necessary to adjust the dosage of Cyclosporine while treating it with Futsis, since there is an increase in plasma concentrations of the first drug.
In practice, there was no decrease in efficiencythe effects of hormonal contraceptives while taking with "Futsis." If Rifabutin is being treated, then adding fluconazole can lead to the development of inflammatory diseases of the choroid.
In patients with diabetes mellitus, taking Fucis helps to increase the period of sulfonylurea elimination, therefore there is a risk of hypoglycemia.
Patients suffering from kidney disease should carefully approach the treatment with this drug, as there is a danger when taking Tacrolimus while enhancing nephrotoxicity.
Absorption of the drug is independent of food intake or antacid preparations.
We have already considered side effects that may occur during therapy with this drug. This does not mean that they will certainly appear, but it is necessary to know about them.
But there are still some special instructions forthe use of Futsis. If the patient suffers from serious liver diseases, then you should not take risks when prescribing treatment with this drug. There were cases when such therapy ended in death, as toxic liver damage began.
The hepatoxic effect is reversible, and if you notice and cancel the drug on time, then all indicators return to normal.
Futsis can provoke anaphylactic reactions in some patients, therefore, patients from this risk group must be kept under medical supervision.
AIDS patients are most often exposedthe development of skin reactions that occur in a fairly severe form. If the appearance of a rash on the body is associated with treatment with Futsis, then its reception must be canceled.
If rashes appear in patients with invasive systemic fungal infections, careful monitoring is necessary. And with the development of erythema multiforme, therapy should be discontinued.
In patients with work problemsthe cardiovascular system, the use of this drug can provoke an increase in the cardiogram of the QT interval. In addition, ventricular flutter may be observed. Most often, such undesirable manifestations were diagnosed in patients with organic heart diseases, electrolyte imbalances. If there is such a danger, then treatment should be carried out with great care, and if possible, it is necessary to think about replacing the drug.
If there are diseases of the liver and kidneys, even inhistory, then, before proceeding with therapy "Futsis", it is worth getting a consultation with your doctor. If a “Fucis” gel is prescribed, the instructions for use clarify that the desired effect will be achieved a little later than during treatment with the pills.
If after the start of therapy severaldays, and there is no improvement in the condition, it is worth informing the doctor about it. Maybe it happened that the fungi were determined incorrectly, and therefore the drug does not have the desired effect.
Any disease, even at first glancesimple, requires a thorough approach to treatment. Only a correctly selected drug can give a 100% guarantee of getting rid of the disease. Do not self-medicate, sometimes it is expensive for health.
