The drug "Ketonal DUO" (tablets), the price of whichfluctuates within 300 rubles., refers to antipyretic, anti-inflammatory and analgesic agents. The drug is characterized by a double - fast and long - action. After taking the medicine, it is absorbed from the digestive tract well enough. The total bioavailability, which is 90%, does not affect the intake of food. Approximately two hours after ingestion, the maximum concentration of the drug is noted. The agent is characterized by the ability to penetrate well into the synovial fluid, where it persists for a minimum of thirty hours. Decay of the medicine occurs in the liver, excretion - through the kidneys.
Means "Ketonal DUO" (tablets). Instructions for use. Indications
The drug is prescribed as a symptomatictherapy of inflammatory and painful processes of different nature. The indications include degenerative diseases in the locomotor apparatus: seronegative, Bechterew's disease (ankylosing spondylitis), psoriatic, reactive, rheumatoid arthritis. The drug Ketonal DUO (pills) is recommended for gout, osteoarthrosis, pseudogout. Indications include the manifestations of pain syndrome against tendonitis, neuralgia, radiculitis, bursitis, as well as headaches, post-traumatic and post-operative pain, and soreness in oncology.
Contraindications
Ketonal DUO tablets are not prescribed forbronchial asthma, urticaria or rhinitis in history, hypersensitivity to components and other NSAIDs, peptic ulcer disease, Crohn's disease in the acute stage, hemophilia and other disorders in the clotting system, kidney and liver failure. The drug is not prescribed for patients after coronary artery bypass grafting, during pregnancy, with cerebrovascular, gastrointestinal and other bleeding, during lactation. The drug is contraindicated in children up to fifteen years old, patients with ulcerative colitis. Caution is shown in diabetes mellitus, peripheral arterial pathologies, cerebrovascular or cardiovascular diseases of severe course, arterial hypertension, history of bronchial asthma, chronic dyspepsia. Correction of the dose may be required with concomitant treatment with antiaggregants, anticoagulants, oral glucocorticosteroids, with prolonged intake of NSAIDs.
The drug "Ketonal DUO" (tablets). Instructions for use. Side effects
During treatment, disorders are likelyliver, kidney, abdominal pain, stomatitis, anaphylactic swelling, gastrointestinal bleeding, speech disorders, hallucinations (when taken in large doses). Medication can cause dizziness, bronchospasm, rhinitis, hematuria, nephrotic syndrome, peripheral puffiness and other negative consequences.
Dosing regimen
Ketonal DUO (pills) is recommended for patients with 15 years of age at 150 mg / day. The medicine is taken after a meal or with food. A day is not allowed to take more than 200 mg.