"Prozerin" (injections) is a synthetic drug, the main active ingredient in which is neostigmine methyl sulfate.
This drug has a pronouncedanticholinesterase activity, and therefore, after its application, the transfer of excitation from the nerve to the skeletal muscle is improved, all cholinergic effects are enhanced in the internal organs and the eye, and also the motility of the gastrointestinal tract is increased, the bronchial tone, the bladder tone and the secretion of the endocrine glands increase.
The drug "Proserin" is produced not only in the form of a solution for injection, but also in the form of tablets, granules, from which a suspension for oral administration (for children) is prepared.
Indications for use
This drug is used whenpresence of myasthenia gravis, paralysis and paresis, with violations of motor activity after brain trauma, neuritis, after encephalitis, poliomyelitis and tuberculosis meningitis.
Also it is used when necessarythe treatment of optic atrophy, to reduce intraocular pressure, which increases with glaucoma, and, if necessary, narrowing of the pupil. With these diseases, the drug is used in the form of eye drops.
The agent "Proserin" (injections) is used forstimulation of labor, and it also has an analgesic effect. Often the drug is used in therapy, where it is used to treat atony of the stomach, bladder and intestines, it is taken internally.
The drug "Proserin" injections, as well as other forms of the said drug, is used exclusively on the prescription of the doctor, and to allow its independent use is prohibited.
If the drug is administered orally, then its dose foradult is from one-hundredth to fifteen hundredths of a gram and is taken up to 3 times a day. For children under the age of ten, one thousandth of a gram for each subsequent year, but not more than 0.01 g per day.
The drug "Proserin" (injections) can be administered assubcutaneously, and intramuscularly in an amount of 1 ml of 0.05% solution, children are injected with one tenth of a ml for each year, but not more than 0.75 milliliters, all carried out one or two times. The total duration of treatment depends on the severity of the disease and can be from 15 to 40 days, and in some cases even longer.
If there is a weak labor activity, thenthe drug "Proserin" (ampoules) should be used for subcutaneous injections and at the same time the "Atropine" agent is administered. This is done only once at the first intake or injection. Also, the drug is taken orally in an amount of 0.003 g every 40 minutes to 6 times, and injections are made with 0.05% solution 2 times in an hour of 1.0 ml.
For an adult, the maximum daily dosethe preparation is 0.05 grams, and the single dose should not exceed fifteen hundredths of a gram. As for injections, the maximum dose per day is 0.006 g, a single dose of not more than two thousandths of a gram.
Possible side effects
After the application of this drug may appear bradycardia, diarrhea, nausea, lower blood pressure, increased bronchial secretion, general weakness and allergic reactions.
If a person has diarrhea and abdominal pain, as well as torrential perspiration, this indicates a toxic effect of the drug "Proserin". In such cases, the drug "Atropine" is injected subcutaneously.
You can not use the medicine in the presence of epilepsy, increased muscle tone, bronchial asthma, angina pectoris, atherosclerosis and intolerance of this drug.
The drug "Proserin": reviews
Well respond about this drug people who suffer from myasthenia gravis, because it is with his help that there is ongoing supportive therapy.
The attitude of patients to the "Proserin"it is ambiguous if some make regular injections, others resort to using it only in rare cases, and some do not tolerate it at all. As a side effect, many patients note the appearance of both dry mouth, and profuse salivation and seizures.
