Levomycetin (eye drops) is referred to asantibiotics with a wide spectrum of action. This drug is intended for local ophthalmic use. Levomycetin (eye drops) is active against many bacteria, including gram-negative and gram-positive, rickettsia and mycoplasmas. This, in turn, allows its use in the treatment and prevention of eye diseases (blepharitis, conjunctivitis, keratitis and others).
Levomycetin (eye drops) is available in five or ten milliliters in plastic or glass bottles.
The active substance in it is chloramphenicol 0.25%. As auxiliary substances in the composition includes purified water, boric acid.
Levomycetin (eye drops) is effective against sulfonamides, penicillins and tetracyclines resistant bacteria.
Pharmacological action of the drug is directed to the fight against microbes and is associated with a violation of the formation of the necessary substances in microorganisms sensitive to the effects of sulfacetamide.
After instillation, the process of absorption of a part of the drug occurs, both into the inner region of the eye, and systemically. The medicine penetrates well into the watery eye area.
Drops for the eyes "Levomycetin" apply to the conjunctival cavity from four to twelve times a day.
The drug is not recommended for use in cases of detection of hypersensitivity to it, chronic and acute deficiency of the kidneys or liver, in case of hemopoiesis and porphyria.
When topical application of the drug cases of overdose in practice was not observed.
Side effects of the drug mayIncrease in a combination of its use with blood-depressant medications, as well as with radiation therapy. When using it with cephalosporins, phenobarbital, penicillins, lincomycin, phenytoin and erythromycin, there is a mutual decrease in efficacy.
"Levomycetin-dia" (eye drops) is possibleapply during pregnancy if the therapeutic effect is higher than the potential risk to the child. It should be noted that there is no strictly controlled and adequate research in the process of using the drug during the antenatal period. As a result, the chloramphenicol's ability to penetrate the placenta must be considered when it is prescribed. Local application of the drug may trigger absorption. Ingestion facilitates the penetration of the drug into breast milk. As a result, serious adverse events may occur in breastfed babies. In this regard, the breastfeeding woman should refuse either breastfeeding or the use of the drug.
Side-effects caused by taking the drug,manifested systemic disorders of the digestive system. These include nausea, dyspepsia, vomiting, dysbiosis, diarrhea, and irritation of the mucous throat and mouth. The drug can have a negative impact on the work of the cardiovascular system. In this case, thrombocytopenia, leukopenia, reticulocytopenia, agranulocytosis, hypogemoglobinaemia, aplastic anemia can be observed. There may be disorders of the nervous system, expressed in psychomotor disorders, impaired consciousness, depression, optic neuritis, delirium, taste disturbance, headache, auditory or visual hallucinations. The drug may cause allergies. Other side effects include secondary fungal infection, dermatitis, in children under one year of cardiovascular collapse.
The medication should be accompanied by regular monitoring of the picture of peripheral blood.
Storage of the drug should be done only in a place protected from light (shaded). The ambient temperature should be below 25 ° C.
